Guoyuan Yang

Best Publications

• The biphasic function of microglia in ischemic stroke.

  Yuanyuan Ma;Jixian Wang;Yongting Wang;Guo-Yuan Yang

  745
  Citations

• Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

  G Yang;P H Chan;J Chen;E Carlson

  685
  Citations

• M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124.

  Yaying Song;Zongwei Li;Tingting He;Meijie Qu

  456
  Citations

• Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury.

  Guo-Yuan Yang;Yong-Jie Zhao;Beverly L Davidson;A.Lorris Betz

  232
  Citations

• CXCR4 Antagonist AMD3100 Protects Blood–Brain Barrier Integrity and Reduces Inflammatory Response After Focal Ischemia in Mice

  Jun Huang;Yaning Li;Yaohui Tang;Guanghui Tang

  220
  Citations

• Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion

  Yanqun Liu;Guanghui Tang;Yaning Li;Yang Wang

  216
  Citations

• M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice

  Zongwei Li;Yaying Song;Tingting He;Ruoxue Wen

  193
  Citations

• Abnormal Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Brain Arteriovenous Malformations

  Tomoki Hashimoto;Gen Wen;Michael T. Lawton;Nancy J. Boudreau

  192
  Citations

• Attenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist

  Tetsuya Masada;Ya Hua;Guohua Xi;Guo-Yuan Yang

  176
  Citations

• Tumor necrosis factor alpha expression produces increased blood–brain barrier permeability following temporary focal cerebral ischemia in mice

  Guo-Yuan Yang;Chao Gong;Chao Gong;Zhen Qin;Xiao-Hong Liu

  174
  Citations

• Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia.

  Zhi-Qiu Wang;Du-Chu Wu;Feng-Ping Huang;Guo-Yuan Yang

  172
  Citations

• M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice

  Unknown

  170
  Citations

• Insulin Growth Factor-1 Gene Transfer Enhances Neurovascular Remodeling and Improves Long-Term Stroke Outcome in Mice

  Wei Zhu;Yongfeng Fan;Tim Frenzel;Mehdi Gasmi

  157
  Citations

• Preischemic But Not Postischemic Zinc Protoporphyrin Treatment Reduces Infarct Size and Edema Accumulation After Temporary Focal Cerebral Ischemia in Rats

  Chitoshi Kadoya;Edward F. Domino;Guo-Yuan Yang;Joseph D. Stern

  156
  Citations

• Blocking C3d+/GFAP+ A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke

  Unknown

  155
  Citations

• Mesenchymal Stem Cells Maintain Blood-Brain Barrier Integrity by Inhibiting Aquaporin-4 Upregulation After Cerebral Ischemia

  Guanghui Tang;Yanqun Liu;Zhijun Zhang;Yifan Lu

  155
  Citations

• Melatonin Pretreatment Improves the Survival and Function of Transplanted Mesenchymal Stem Cells after Focal Cerebral Ischemia.

  Yaohui Tang;Beibei Cai;Falei Yuan;Xiaosong He

  142
  Citations

• ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway

  Unknown

  138
  Citations

• Edema, cation content, and ATPase activity after middle cerebral artery occlusion in rats.

  G Y Yang;S F Chen;H Kinouchi;P H Chan

  137
  Citations

• Blood-Brain Barrier Disruption Induced Cognitive Impairment Is Associated With Increase of Inflammatory Cytokine

  Jieli Geng;Liping Wang;Linyuan Zhang;Chuan Qin

  125
  Citations