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Genetics

D-Index
47
Citations
16225
World Ranking
4086
National Ranking
1760

Overview

Bruce T. Lahn is affiliated with the University of Chicago in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with notable contributions in subfields including Molecular Biology, Biomedical Engineering, Sociology and Political Science, Experimental and Cognitive Psychology, and Plant Science.

The scientist's work covers a range of specialized topics, prominently featuring:

  • Renal and related cancers
  • Evolutionary Game Theory and Cooperation
  • Evolutionary Psychology and Human Behavior
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Chromosomal and Genetic Variations

Among Bruce T. Lahn's recent publications are the following papers:

  • "Social dominance hierarchy: toward a genetic and evolutionary understanding" (2020), published in Cell Research
  • "Capacity to erase gene occlusion is a defining feature distinguishing naive from primed pluripotency" (2021), featured in bioRxiv (Cold Spring Harbor Laboratory)
  • "Mechanistic basis of lineage restriction" (2024), appearing in bioRxiv (Cold Spring Harbor Laboratory)
  • "Safety and Efficacy of Vesemnogene Lantuparvovec, an AAV-Based Gene Therapy in Young Children Under 24 Months with Spinal Muscular Atrophy in Low- and-Middle-Income Countries. Second Interim Report (August 2025)" (2025), published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Prevalence of errors in lab-made plasmids across the globe." (2025), listed in PubMed

The frequent venues for publication include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Research
  • PubMed

Bruce T. Lahn has collaborated multiple times with several researchers, including:

  • Kara M. Foshay
  • Jae-Hyun Lee
  • Croydon J. Fernandes
  • Bohou Wu
  • Guoping Fan

Best Publications

  • Geometric cues for directing the differentiation of mesenchymal stem cells.

    Kristopher A. Kilian;Branimir Bugarija;Bruce T. Lahn;Milan Mrksich

  • Evolutionary and biomedical insights from the rhesus macaque genome

    Richard A. Gibbs;Jeffrey Rogers

  • Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

    Chun Xiao Song;Keith E. Szulwach;Ye Fu;Qing Dai

  • Four Evolutionary Strata on the Human X Chromosome

    Bruce T. Lahn;David C. Page

  • FUNCTIONAL COHERENCE OF THE HUMAN Y CHROMOSOME

    Bruce T. Lahn;David C. Page

  • Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans

    Patrick D. Evans;Sandra L. Gilbert;Nitzan Mekel-Bobrov;Eric J. Vallender

  • Systematic comparison of constitutive promoters and the doxycycline-inducible promoter.

    Jane Yuxia Qin;Jane Yuxia Qin;Li Zhang;Kayla L. Clift;Imge Hulur

  • Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens.

    Nitzan Mekel-Bobrov;Sandra L. Gilbert;Patrick D. Evans;Eric J. Vallender

  • Accelerated Evolution of Nervous System Genes in the Origin of Homo sapiens

    Steve Dorus;Eric J. Vallender;Eric J. Vallender;Patrick D. Evans;Patrick D. Evans;Jeffrey R. Anderson

  • Nestin is required for the proper self-renewal of neural stem cells.

    Donghyun Park;Donghyun Park;Andy Peng Xiang;Frank Fuxiang Mao;Frank Fuxiang Mao;Li Zhang

  • Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans

    Patrick D. Evans;Jeffrey R. Anderson;Eric J. Vallender;Sandra L. Gilbert

  • The human Y chromosome, in the light of evolution.

    Bruce T. Lahn;Nathaniel M. Pearson;Nathaniel M. Pearson;Karin Jegalian

  • Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity

    Steve Dorus;Steve Dorus;Patrick D Evans;Patrick D Evans;Gerald J Wyckoff;Gerald J Wyckoff;Sun Shim Choi

  • Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.

    Bruce T Lahn;David C Page

  • Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis

    Bruce T. Lahn;Zhao Lan Tang;Jianxin Zhou;Robert J. Barndt

  • Positive selection on the human genome

    Eric J. Vallender;Bruce T. Lahn

  • Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size

    Patrick D. Evans;Jeffrey R. Anderson;Eric J. Vallender;Sun Shim Choi

  • Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage

    Patrick D. Evans;Nitzan Mekel-Bobrov;Eric J. Vallender;Richard R. Hudson

  • Genetic links between brain development and brain evolution.

    Sandra L. Gilbert;William B. Dobyns;Bruce T. Lahn

  • Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction

    Mei Hua Jiang;Bing Cai;Ying Tuo;Jiancheng Wang

Frequent Co-Authors

Rui Chen
Rui Chen Southern University of Science and Technology
Lucy A. Godley
Lucy A. Godley University of Chicago
Richard R. Hudson
Richard R. Hudson University of Chicago
Sarah A. Tishkoff
Sarah A. Tishkoff University of Pennsylvania
William B. Dobyns
William B. Dobyns University of Minnesota
David Haussler
David Haussler University of California, Santa Cruz
Leah Rae Donahue
Leah Rae Donahue The Jackson Laboratory
Roderick T. Bronson
Roderick T. Bronson Harvard University
Jinchuan Xing
Jinchuan Xing Rutgers, The State University of New Jersey

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