Efficacy and Mechanism Evaluation

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Top Publications

• Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs

  Manu Shankar-Hari;Manu Shankar-Hari;Shalini Santhakumaran;A Toby Prevost;Josie K Ward

  (2021)
  16 Citations

• Mini-combined test compared with NICE guidelines for early risk-assessment for pre-eclampsia: the SPREE diagnostic accuracy study

  Liona C Poon;David Wright;Steve Thornton;Ranjit Akolekar

  (2020)
  14 Citations

• Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

  Floriana De Angelis;Peter Connick;Richard A Parker;Domenico Plantone

  (2020)
  14 Citations

• Digitally supported CBT to reduce paranoia and improve reasoning for people with schizophrenia-spectrum psychosis: the SlowMo RCT

  Philippa Garety;Philippa Garety;Thomas Ward;Thomas Ward;Richard Emsley;Kathryn Greenwood;Kathryn Greenwood

  (2021)
  12 Citations

• Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer’s disease: the MADE Phase II, three-arm RCT

  Robert Howard;Olga Zubko;Richard Gray;Rosie Bradley

  (2020)
  12 Citations

• Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT

  Alexander Dimitri Miras;Anna Kamocka;Tricia Tan;Belén Pérez-Pevida

  (2021)
  10 Citations

• Lactoferrin impact on gut microbiota in preterm infants with late-onset sepsis or necrotising enterocolitis: the MAGPIE mechanisms of action study

  Nicholas Embleton;Janet Berrington;Stephen Cummings;Jon Dorling

  (2021)
  10 Citations