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Neuroscience

D-Index
87
Citations
38678
World Ranking
1234
National Ranking
43

Overview

G. Di Chiara is affiliated with the University of Cagliari in Italy and has contributed extensively to the field of neuroscience, with a particular focus on cellular and molecular neuroscience. Their research spans several subfields including molecular biology, pharmacology, clinical psychology, and surgery. The main topics addressed in their work include neurotransmitter receptor influence on behavior, neuropeptides and animal physiology, receptor mechanisms and signaling, cannabis and cannabinoid research, neuroscience and neuropharmacology research, pharmacological receptor mechanisms and effects, and obsessive-compulsive spectrum disorders.

Frequent coauthors in their publications include Maria Antonietta De Luca, Rafaela Mostallino, M. Paola Castelli, Graziella Tocco, and Antonio Laus.

They have published notably in venues such as Neuropharmacology, British Journal of Pharmacology, Addiction Biology, Archiv der Pharmazie, and Pharmacology Biochemistry and Behavior. Among these, Neuropharmacology, British Journal of Pharmacology, and Addiction Biology are the most frequent journals where their work appears.

Recent publications authored or coauthored by G. Di Chiara include the following:

  • Pharmacological characterization of novel synthetic opioids: Isotonitazene, metonitazene, and piperidylthiambutene as potent μ-opioid receptor agonists (2022, Neuropharmacology)
  • Adolescent cannabis exposure increases heroin reinforcement in rats genetically vulnerable to addiction (2020, Neuropharmacology)
  • Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates (2021, British Journal of Pharmacology)
  • Does compulsion explain addiction? (2024, Addiction Biology)
  • 3-[3-(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone-derived novel class of MOR-antagonists (2022, Archiv der Pharmazie)

Best Publications

  • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

    G Di Chiara;A Imperato

  • Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

    F. E. Pontieri;G. Tanda;F. Orzi;G. Di Chiara

  • Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ1 Opioid Receptor Mechanism

    Gianluigi Tanda;Francesco E. Pontieri;Gaetano Di Chiara

  • Nucleus accumbens shell and core dopamine: differential role in behavior and addiction

    Gaetano Di Chiara

  • Dopamine and Drug Addiction: The Nucleus Accumbens Shell Connection

    Gaetano Di Chiara;Valentina Bassareo;Sandro Fenu;Maria Antonietta De Luca

  • Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

    G Di Chiara;A Imperato

  • Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol.

    A Imperato;G Di Chiara

  • Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens

    F. E. Pontieri;G. Tanda;G. Di Chiara

  • The role of dopamine in drug abuse viewed from the perspective of its role in motivation

    Gaetano Di Chiara

  • Role of dopamine in the behavioural actions of nicotine related to addiction

    Gaetano Di Chiara

  • Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats.

    A Imperato;A Mulas;G Di Chiara

  • Neurobiology of opiate abuse

    Gaetano Di Chiara;R. Alan North

  • Drug addiction as dopamine-dependent associative learning disorder

    Gaetano Di Chiara

  • Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats.

    E. Carboni;A. Imperato;L. Perezzani;G. Di Chiara

  • Trans-striatal dialysis coupled to reverse phase high performance liquid chromatography with electrochemical detection: a new method for the study of the in vivo release of endogenous dopamine and metabolites

    A Imperato;G Di Chiara

  • Evidence for dopamine receptors mediating sedation in the mouse brain.

    G. Di Chiara;M. L. Porceddu;L. Vargiu;A. Argiolas

  • Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

    Gaetano Di Chiara;Micaela Morelli;Silvana Consolo

  • Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals.

    E. Carboni;G. L. Tanda;R. Frau;G. Di Chiara

  • Evidence for a GABAergic projection from the substantia nigra to the ventromedial thalamus and to the superior colliculus of the rat.

    G. Di Chiara;M.L. Porceddu;M. Morelli;M.L. Mulas

  • Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments.

    V Bassareo;G Di Chiara

  • A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use

    Gaetano Di Chiara

  • Dopamine release and metabolism in awake rats after systemic neuroleptics as studied by trans-striatal dialysis

    A Imperato;G Di Chiara

Frequent Co-Authors

Micaela Morelli
Micaela Morelli University of Cagliari
Roberto Frau
Roberto Frau University of Cagliari
Francesco E. Pontieri
Francesco E. Pontieri Sapienza University of Rome
Annalisa Pinna
Annalisa Pinna National Research Council (CNR)
Marcello Solinas
Marcello Solinas University of Poitiers
Francesco Orzi
Francesco Orzi Sapienza University of Rome
Stefano Ruggieri
Stefano Ruggieri Sapienza University of Rome
Maurizio Popoli
Maurizio Popoli University of Milan
Timothy J Schallert
Timothy J Schallert The University of Texas at Austin
Antonio Argiolas
Antonio Argiolas University of Cagliari

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