D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 88 Citations 28,547 153 World Ranking 1215 National Ranking 727

Research.com Recognitions

Awards & Achievements

1992 - Fellow of the American Association for the Advancement of Science (AAAS)

1980 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His main research concerns Biochemistry, Molecular biology, Peptide sequence, Gene and Genetics. His biological study spans a wide range of topics, including Clotting factor and Thrombomodulin. His studies deal with areas such as Stop codon, Alpha chain, Factor IX, cDNA library and Stuart Factor as well as Molecular biology.

Earl W. Davie interconnects Amino acid, Peptide bond, Factor VII and Protein structure in the investigation of issues within Peptide sequence. The concepts of his Amino acid study are interwoven with issues in Factor XIIa, Prekallikrein and Edman degradation. His Genetics research includes elements of Factor XI, Plasma levels and Coagulopathy.

His most cited work include:

  • The coagulation cascade: initiation, maintenance, and regulation (1558 citations)
  • WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING. (847 citations)
  • Cloning and characterization of human protease-activated receptor 4 (744 citations)

What are the main themes of his work throughout his whole career to date?

Earl W. Davie focuses on Biochemistry, Molecular biology, Peptide sequence, Amino acid and Complementary DNA. The Biochemistry study combines topics in areas such as Factor X, Thrombin and Coagulation. His work deals with themes such as Nucleic acid sequence, Recombinant DNA, Base pair, Gene and Sequence analysis, which intersect with Molecular biology.

His Peptide sequence study integrates concerns from other disciplines, such as Peptide bond, Immunoglobulin light chain, Protein structure and Serine protease. His research in Amino acid intersects with topics in Edman degradation and Signal peptide. His Complementary DNA research is multidisciplinary, incorporating perspectives in Plasmid, DNA and Stop codon.

He most often published in these fields:

  • Biochemistry (52.82%)
  • Molecular biology (35.38%)
  • Peptide sequence (26.67%)

What were the highlights of his more recent work (between 1993-2013)?

  • Biochemistry (52.82%)
  • Molecular biology (35.38%)
  • Peptide sequence (26.67%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Biochemistry, Molecular biology, Peptide sequence, Amino acid and Thrombin. In the subject of general Biochemistry, his work in Trypsin, Plasmin and Gene expression is often linked to Transmembrane protein and Matrix gla protein, thereby combining diverse domains of study. Earl W. Davie has included themes like Gene and Binding site in his Molecular biology study.

His work on cDNA library as part of general Peptide sequence study is frequently linked to Factor V, therefore connecting diverse disciplines of science. His studies in Amino acid integrate themes in fields like Complementary DNA and Protein primary structure. His study on Thrombin also encompasses disciplines like

  • Proteases that connect with fields like Coagulation and Serine protease,
  • Platelet activation and related Endocrinology and Clotting time.

Between 1993 and 2013, his most popular works were:

  • Cloning and characterization of human protease-activated receptor 4 (744 citations)
  • Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation (282 citations)
  • Structure of the C2 domain of human factor VIII at 1.5 Å resolution (282 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

The scientist’s investigation covers issues in Biochemistry, Serine protease, Thrombin, Trypsin and Protein structure. His studies in Peptide sequence and Amino acid are all subfields of Biochemistry research. His Peptide sequence study incorporates themes from Sequence analysis and Carboxyglutamic acid.

As a part of the same scientific study, Earl W. Davie usually deals with the Serine protease, concentrating on Proteases and frequently concerns with Plasminogen activator, Zymogen and Plasmin. His work in Thrombin addresses issues such as Platelet activation, which are connected to fields such as Endocrinology and Clotting time. His Trypsin research integrates issues from Molecular biology and Protease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The coagulation cascade: initiation, maintenance, and regulation

Earl W. Davie;Kazuo Fujikawa;Walter Kisiel.
Biochemistry (1991)

2539 Citations

WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.

Earl W. Davie;Oscar D. Ratnoff.
Science (1964)

1344 Citations

Cloning and characterization of human protease-activated receptor 4

Wen-feng Xu;Henrik Andersen;Theodore E. Whitmore;Scott R. Presnell.
Proceedings of the National Academy of Sciences of the United States of America (1998)

966 Citations

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B).

Shinji Yoshitake;Barbara G. Schach;Donald C. Foster;Earl W. Davie.
Biochemistry (1985)

920 Citations

A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S.

Richard G. Di Scipio;Mark A. Hermodson;Stanley G. Yates;Earl W. Davie.
Biochemistry (1977)

774 Citations

Anticoagulant properties of bovine plasma protein C following activation by thrombin.

Walter Kisiel;William M. Canfield;Lowell H. Ericsson;Earl W. Davie.
Biochemistry (1977)

697 Citations

Preparation and properties of bovine factor VIII (antihemophilic factor)

Gordon A. Vehar;Earl W. Davie.
Biochemistry (1980)

669 Citations

Characterization of a cDNA coding for human factor VII

Steven P. Leytus;Dominic W. Chung;Walter Kisiel;Kotoku Kurachi.
Proceedings of the National Academy of Sciences of the United States of America (1984)

633 Citations

Isolation and characterization of a cDNA coding for human factor IX

Kotoku Kurachi;Earl W. Davie.
Proceedings of the National Academy of Sciences of the United States of America (1982)

570 Citations

Complete sequence of the cDNA for human .alpha.1-antitrypsin and the gene for the S variant

George L. Long;T. Chandra;Savio L. C. Woo;Earl W. Davie.
Biochemistry (1984)

509 Citations

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