D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 24,022 134 World Ranking 2496 National Ranking 188
Medicine D-index 82 Citations 27,527 145 World Ranking 8648 National Ranking 400

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Virology, Virus, Primary effusion lymphoma, Cancer and Latent Nuclear Antigen. His Virology research integrates issues from Lymphoproliferative disorders and Chemokine receptor. The concepts of his Virus study are interwoven with issues in miR-132, Regulation of gene expression, Antibody and Sarcoma.

His research integrates issues of Progressive disease, Acquired immunodeficiency syndrome and Renal cell carcinoma in his study of Cancer. His work carried out in the field of Latent Nuclear Antigen brings together such families of science as Molecular mimicry, Cytokine, Macrophage inflammatory protein, Kaposi's sarcoma-associated herpesvirus and Retinoblastoma protein. His research in Kaposi's sarcoma-associated herpesvirus intersects with topics in Cancer research and Interferon regulatory factors.

His most cited work include:

  • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing (1203 citations)
  • Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV (825 citations)
  • Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen (574 citations)

What are the main themes of his work throughout his whole career to date?

Chris Boshoff focuses on Virology, Cancer research, Immunology, Cancer and Kaposi's sarcoma. Virology is a component of his Virus, Kaposi's sarcoma-associated herpesvirus, Primary effusion lymphoma, Herpesviridae and Latent Nuclear Antigen studies. His Primary effusion lymphoma study incorporates themes from Molecular biology and Small hairpin RNA.

His Cancer research research is multidisciplinary, relying on both DNA methylation, Bioinformatics, Reprogramming, Gene silencing and Cell type. His biological study deals with issues like Acquired immunodeficiency syndrome, which deal with fields such as Seroprevalence. His Cancer research includes elements of Epigenetics and Oncology.

He most often published in these fields:

  • Virology (43.31%)
  • Cancer research (26.75%)
  • Immunology (20.38%)

What were the highlights of his more recent work (between 2012-2014)?

  • Cancer research (26.75%)
  • Virology (43.31%)
  • Head and neck squamous-cell carcinoma (2.55%)

In recent papers he was focusing on the following fields of study:

Chris Boshoff mostly deals with Cancer research, Virology, Head and neck squamous-cell carcinoma, Cell biology and Genetics. His studies in Cancer research integrate themes in fields like Cell, Sarcoma, Bioinformatics and Human genetics. Chris Boshoff studies Kaposi's sarcoma-associated herpesvirus, a branch of Virology.

His Head and neck squamous-cell carcinoma research is multidisciplinary, incorporating perspectives in Methylation, Differentially methylated regions, DNA methylation, Breast cancer and PI3K/AKT/mTOR pathway. His work deals with themes such as microRNA and Downregulation and upregulation, which intersect with Cell biology. His work in Downregulation and upregulation addresses subjects such as Transcription factor, which are connected to disciplines such as Cancer.

Between 2012 and 2014, his most popular works were:

  • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing (1203 citations)
  • APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development (222 citations)
  • Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. (158 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Genetics, Head and neck squamous-cell carcinoma, Bioinformatics, Cancer research and Cancer. His work in Minor histocompatibility antigen, APOBEC, Cytidine deaminase, Papillomaviridae and Cytosine is related to Genetics. His Head and neck squamous-cell carcinoma research includes themes of Differentially methylated regions, CpG Island Methylator Phenotype, DNA methylation, Tumor progression and Epigenetics.

His Bioinformatics research is multidisciplinary, incorporating elements of Methylation, Disease, Cyclin D1, PI3K/AKT/mTOR pathway and Human genetics. His study in Cancer research is interdisciplinary in nature, drawing from both Immunohistochemistry, Human Papillomavirus Positive, CDKN2A and Methylated DNA immunoprecipitation. Chris Boshoff interconnects Allele frequency and Sequence analysis, Gene, DNA sequencing in the investigation of issues within Cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Garrett M Frampton;Alex Fichtenholtz;Geoff A Otto;Kai Wang.
Nature Biotechnology (2013)

1507 Citations

Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV

Patrick S. Moore;Chris Boshoff;Robin A. Weiss;Yuan Chang.
Science (1996)

1039 Citations

HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma.

Nicolas Dupin;Tim L. Diss;Paul Kellam;Micheline Tulliez.
Blood (2000)

749 Citations

Kaposi's sarcoma and its associated herpesvirus

Enrique A. Mesri;Ethel Cesarman;Chris Boshoff.
Nature Reviews Cancer (2010)

689 Citations

Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen

Guy R Simpson;Thomas F Schulz;Denise Whitby;Pamela M Cook.
The Lancet (1996)

657 Citations

The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells

Stoyan A. Radkov;Paul Kellam;Chris Boshoff.
Nature Medicine (2000)

582 Citations

Kaposi's Sarcoma-Associated Herpesvirus

Chris Boshoff;Robin A. Weiss.
Advances in Cancer Research (1997)

543 Citations

AIDS-related malignancies.

Chris Boshoff;Robin Weiss.
Nature Reviews Cancer (2002)

538 Citations

Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer.

T Eisen;T Eisen;C Boshoff;C Boshoff;I Mak;F Sapunar.
British Journal of Cancer (2000)

537 Citations

Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma

Hsei-Wei Wang;Matthew W B Trotter;Dimitrios Lagos;Dimitra Bourboulia.
Nature Genetics (2004)

507 Citations

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