His primary scientific interests are in Virology, Virus, Primary effusion lymphoma, Cancer and Latent Nuclear Antigen. His Virology research integrates issues from Lymphoproliferative disorders and Chemokine receptor. The concepts of his Virus study are interwoven with issues in miR-132, Regulation of gene expression, Antibody and Sarcoma.
His research integrates issues of Progressive disease, Acquired immunodeficiency syndrome and Renal cell carcinoma in his study of Cancer. His work carried out in the field of Latent Nuclear Antigen brings together such families of science as Molecular mimicry, Cytokine, Macrophage inflammatory protein, Kaposi's sarcoma-associated herpesvirus and Retinoblastoma protein. His research in Kaposi's sarcoma-associated herpesvirus intersects with topics in Cancer research and Interferon regulatory factors.
Chris Boshoff focuses on Virology, Cancer research, Immunology, Cancer and Kaposi's sarcoma. Virology is a component of his Virus, Kaposi's sarcoma-associated herpesvirus, Primary effusion lymphoma, Herpesviridae and Latent Nuclear Antigen studies. His Primary effusion lymphoma study incorporates themes from Molecular biology and Small hairpin RNA.
His Cancer research research is multidisciplinary, relying on both DNA methylation, Bioinformatics, Reprogramming, Gene silencing and Cell type. His biological study deals with issues like Acquired immunodeficiency syndrome, which deal with fields such as Seroprevalence. His Cancer research includes elements of Epigenetics and Oncology.
Chris Boshoff mostly deals with Cancer research, Virology, Head and neck squamous-cell carcinoma, Cell biology and Genetics. His studies in Cancer research integrate themes in fields like Cell, Sarcoma, Bioinformatics and Human genetics. Chris Boshoff studies Kaposi's sarcoma-associated herpesvirus, a branch of Virology.
His Head and neck squamous-cell carcinoma research is multidisciplinary, incorporating perspectives in Methylation, Differentially methylated regions, DNA methylation, Breast cancer and PI3K/AKT/mTOR pathway. His work deals with themes such as microRNA and Downregulation and upregulation, which intersect with Cell biology. His work in Downregulation and upregulation addresses subjects such as Transcription factor, which are connected to disciplines such as Cancer.
His primary scientific interests are in Genetics, Head and neck squamous-cell carcinoma, Bioinformatics, Cancer research and Cancer. His work in Minor histocompatibility antigen, APOBEC, Cytidine deaminase, Papillomaviridae and Cytosine is related to Genetics. His Head and neck squamous-cell carcinoma research includes themes of Differentially methylated regions, CpG Island Methylator Phenotype, DNA methylation, Tumor progression and Epigenetics.
His Bioinformatics research is multidisciplinary, incorporating elements of Methylation, Disease, Cyclin D1, PI3K/AKT/mTOR pathway and Human genetics. His study in Cancer research is interdisciplinary in nature, drawing from both Immunohistochemistry, Human Papillomavirus Positive, CDKN2A and Methylated DNA immunoprecipitation. Chris Boshoff interconnects Allele frequency and Sequence analysis, Gene, DNA sequencing in the investigation of issues within Cancer.
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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
Garrett M Frampton;Alex Fichtenholtz;Geoff A Otto;Kai Wang.
Nature Biotechnology (2013)
Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV
Patrick S. Moore;Chris Boshoff;Robin A. Weiss;Yuan Chang.
HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma.
Nicolas Dupin;Tim L. Diss;Paul Kellam;Micheline Tulliez.
Kaposi's sarcoma and its associated herpesvirus
Enrique A. Mesri;Ethel Cesarman;Chris Boshoff.
Nature Reviews Cancer (2010)
Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen
Guy R Simpson;Thomas F Schulz;Denise Whitby;Pamela M Cook.
The Lancet (1996)
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells
Stoyan A. Radkov;Paul Kellam;Chris Boshoff.
Nature Medicine (2000)
Kaposi's Sarcoma-Associated Herpesvirus
Chris Boshoff;Robin A. Weiss.
Advances in Cancer Research (1997)
Chris Boshoff;Robin Weiss.
Nature Reviews Cancer (2002)
Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer.
T Eisen;T Eisen;C Boshoff;C Boshoff;I Mak;F Sapunar.
British Journal of Cancer (2000)
Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
Hsei-Wei Wang;Matthew W B Trotter;Dimitrios Lagos;Dimitra Bourboulia.
Nature Genetics (2004)
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