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Chemistry

D-Index
44
Citations
7275
World Ranking
16834
National Ranking
650

Overview

Alessandro Pezzella is affiliated with the University of Naples Federico II in Italy. Their primary field of research is Materials Science, with a focus on subfields including Cell Biology, Biomaterials, Materials Chemistry, Biomedical Engineering, and Nutrition and Dietetics. The research topics largely center on melanin and skin pigmentation, silk-based biomaterials and applications, biochemical analysis and sensing techniques, skin protection and aging, nanoplatforms for cancer theranostics, gold and silver nanoparticles synthesis and applications, and advanced nanomaterials in catalysis.

Pezzella's recent publications reflect these research interests, covering multiple aspects of biomaterials and nanotechnology. Recent papers include:

  • "Melanin and Melanin-Like Hybrid Materials in Regenerative Medicine" (2020, Nanomaterials)
  • "Multifunctional mats by antimicrobial nanoparticles decoration for bioinspired smart wound dressing solutions" (2021, Materials Science and Engineering C)
  • "Albumin-Modified Melanin-Silica Hybrid Nanoparticles Target Breast Cancer Cells via a SPARC-Dependent Mechanism" (2020, Frontiers in Bioengineering and Biotechnology)
  • "Relation between Local Structure, Electric Dipole, and Charge Carrier Dynamics in DHICA Melanin: A Model for Biocompatible Semiconductors" (2020, The Journal of Physical Chemistry Letters)
  • "Bioinspired antibacterial PVA/Melanin-TiO2 hybrid nanoparticles: the role of poly-vinyl-alcohol on their self-assembly and biocide activity" (2021, Colloids and Surfaces B Biointerfaces)

Frequent coauthors collaborating with Pezzella include:

  • Giuseppina Luciani
  • Giulio Pota
  • Giuseppe Vitiello
  • Brigida Silvestri
  • Paola Manini

Pezzella's work is published across a range of journals with repeated appearances in venues such as:

  • Biomaterials Advances
  • Nanomaterials
  • Colloids and Surfaces B Biointerfaces
  • Biomedicines
  • Applied Surface Science

Best Publications

  • Chemical and Structural Diversity in Eumelanins: Unexplored Bio‐Optoelectronic Materials

    Marco d'Ischia;Alessandra Napolitano;Alessandro Pezzella;Paul Meredith

  • Melanins and melanogenesis: from pigment cells to human health and technological applications.

    Marco d'Ischia;Kazumasa Wakamatsu;Fabio Cicoira;Eduardo Di Mauro

  • Melanins and melanogenesis: methods, standards, protocols

    Marco D'Ischia;Kazumasa Wakamatsu;Alessandra Napolitano;Stefania Briganti

  • Protonic and Electronic Transport in Hydrated Thin Films of the Pigment Eumelanin

    Julia Wünsche;Yingxin Deng;Prajwal Kumar;Eduardo Di Mauro

  • Disentangling eumelanin "black chromophore": visible absorption changes as signatures of oxidation state- and aggregation-dependent dynamic interactions in a model water-soluble 5,6-dihydroxyindole polymer.

    Alessandro Pezzella;Alfonso Iadonisi;Silvia Valerio;Lucia Panzella

  • Iron-Mediated Generation of the Neurotoxin 6-Hydroxydopamine Quinone by Reaction of Fatty Acid Hydroperoxides with Dopamine: A Possible Contributory Mechanism for Neuronal Degeneration in Parkinson's Disease

    Alessandro Pezzella;Marco d'Ischia;Alessandra Napolitano;Giovanna Misuraca

  • Melanin Biopolymers: Tailoring Chemical Complexity for Materials Design.

    Marco d'Ischia;Alessandra Napolitano;Alessandro Pezzella;Paul Meredith

  • An integrated approach to the structure of Sepia melanin. Evidence for a high proportion of degraded 5,6-dihydroxyindole-2-carboxylic acid units in the pigment backbone

    Alessandro Pezzella;Marco d'Ischia;Alessandra Napolitano;Anna Palumbo

  • Eumelanin Buildup on the Nanoscale: Aggregate Growth/Assembly and Visible Absorption Development in Biomimetic 5,6-Dihydroxyindole Polymerization.

    Marianna Arzillo;Gaetano Mangiapia;Gaetano Mangiapia;Alessandro Pezzella;Richard K. Heenan

  • Superior Photoprotective Motifs and Mechanisms in Eumelanins Uncovered

    Alice Corani;Annemarie Huijser;Thomas Gustavsson;Dimitra Markovitsi

  • 5,6-dihydroxyindole tetramers with "anomalous" interunit bonding patterns by oxidative coupling of 5,5',6,6'-tetrahydroxy-2,7'-biindolyl: emerging complexities on the way toward an improved model of eumelanin buildup

    Alessandro Pezzella;Lucia Panzella;Anna Natangelo;Marianna Arzillo

  • Short-Lived Quinonoid Species from 5,6-Dihydroxyindole Dimers en Route to Eumelanin Polymers: Integrated Chemical, Pulse Radiolytic, and Quantum Mechanical Investigation

    Alessandro Pezzella;Lucia Panzella;Orlando Crescenzi;Alessandra Napolitano

  • The first 5,6-dihydroxyindole tetramer by oxidation of 5,5',6,6'-tetrahydroxy- 2,4'-biindolyl and an unexpected issue of positional reactivity en route to eumelanin-related polymers.

    Lucia Panzella;Alessandro Pezzella;and Alessandra Napolitano;Marco d'Ischia

  • Generation of the neurotoxin 6-hydroxydopamine by peroxidase/H2O2 oxidation of dopamine.

    Alessandra Napolitano;Orlando Crescenzi;Alessandro Pezzella;Giuseppe Prota

  • Stem cell-compatible eumelanin biointerface fabricated by chemically controlled solid state polymerization

    Alessandro Pezzella;Mario Barra;Anna Musto;Angelica Navarra

  • 5,6-Dihydroxyindoles and Indole-5,6-diones

    Marco d’Ischia;Alessandra Napolitano;Alessandro Pezzella;Edward J. Land

  • Dopaquinone redox exchange with dihydroxyindole and dihydroxyindole carboxylic acid.

    R. Edge;R. Edge;M. D'Ischia;E. J. Land;A. Napolitano

  • Oxidative degradation of melanins to pyrrole acids: A model study

    Alessandra Napolitano;Alessandro Pezzella;M.Rosaria Vincensi;Giuseppe Prota

  • Role of solvent, pH, and molecular size in excited-state deactivation of key eumelanin building blocks: implications for melanin pigment photostability.

    Magdalena Gauden;A Pezzella;L Panzella;M Neves-Petersen

  • Structural Analysis of Synthetic Melanins from 5,6‐Dihydroxyindole by Matrix‐assisted Laser Desorption/Ionization Mass Spectrometry

    Alessandra Napolitano;Alessandro Pezzella;Giuseppe Prota;Roberta Seraglia

Frequent Co-Authors

Marco d'Ischia
Marco d'Ischia University of Naples Federico II
Alessandra Napolitano
Alessandra Napolitano University of Naples Federico II
Lucia Panzella
Lucia Panzella University of Naples Federico II
Giuseppe Prota
Giuseppe Prota University of Naples Federico II
Vincenzo Barone
Vincenzo Barone Scuola Normale Superiore di Pisa
Villy Sundström
Villy Sundström Lund University
Gerardino D'Errico
Gerardino D'Errico University of Naples Federico II
Paul Meredith
Paul Meredith Swansea University
Federico Rosei
Federico Rosei Institut National de la Recherche Scientifique
Fabio Cicoira
Fabio Cicoira Polytechnique Montréal

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