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Letters in Drug Design and Discovery
H-index 7

Letters in Drug Design and Discovery

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 834 44 59 7

Additional Metrics

Number of Best Scientists*: 85
Documents by Best Scientists*: 105
Top 100 Ranked Scientists*: 4
SCIMAGO H-index: 40
SCIMAGO SJR: 0.31
Impact Factor: 1.6

Overview

Top Research Topics at Letters in Drug Design & Discovery?

The journal mainly tackles studies in Combinatorial chemistry, Stereochemistry, Biochemistry, Pharmacology and Organic chemistry. The journal holds forums on Combinatorial chemistry that merges themes from other disciplines such as Design synthesis, Biological evaluation, In vitro and Antimicrobial. Quantitative structure–activity relationship and Docking (molecular) are all topics related to Stereochemistry research discussed.

  • Combinatorial chemistry (23.56%)
  • Stereochemistry (19.23%)
  • Biochemistry (13.59%)

What are the most cited papers published in the journal?

  • Synthesis, Antibacterial Activity of 2,4-Disubstituted Oxazoles and Thiazoles as Bioisosteres (82 citations)
  • Synthesis of Mannich Bases by Two Different Methods and Evaluation of their Acetylcholine Esterase and Carbonic Anhydrase Inhibitory Activities (69 citations)
  • Synthesis and Antifungal Activity of 1,3,4-Thiadiazole Derivatives Containing Pyridine Group (64 citations)

Research areas of the most cited articles at Letters in Drug Design & Discovery:

The most cited papers investigate studies in Stereochemistry, Combinatorial chemistry, Pharmacology, Biochemistry and In vitro. The most cited papers address concerns in the field of Stereochemistry by exploring it in line with topics in Cytotoxic T cell which intersect with Cytotoxicity subjects. While work presented in the published papers provide substantial information on Combinatorial chemistry, it also covers topics in Antibacterial activity, Antimicrobial, Oxadiazole, Pyrazole and Biological evaluation.

What topics the last edition of the journal is best known for?

  • Enzyme
  • Organic chemistry
  • Gene

The previous edition focused in particular on these issues:

The journal generally zeroes in on subjects such as Combinatorial chemistry, In silico, Computational biology, Biochemistry and Drug. Combinatorial chemistry research presented in Letters in Drug Design & Discovery encompasses a variety of subjects, including Pharmacophore, Design synthesis and Quantitative structure–activity relationship. Topics in Design synthesis explored in it were investigated in conjunction with research in Biological evaluation and Stereochemistry.

The study on Stereochemistry presented in the journal intersects with the topics under Inhibitory postsynaptic potential. The journal facilitates discussions on Computational biology that incorporate concepts from other fields like Virtual screening, Docking (molecular), Identification (biology), Drug repositioning and Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Biochemistry study featured in the journal draws parallels with the field of Antimicrobial.

The most cited articles from the last journal are:

  • Unveiling the Anti-tubercular Properties of Biscoumarins, through Biological Evaluation and Docking Studies (3 citations)
  • Bioactive Isolates of Morus Species as Antibacterial Agents and their in-silico Profiling (2 citations)
  • Molecular Docking, DFT Studies and ADMET Simulations for Evaluating Already Approved FDA Drugs as Inhibitors for SARS-Cov-2 RNADependent Polymerase (1 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in Letters in Drug Design & Discovery (based on the number of publications) are:

  • Khalid Mohammed Khan (30 papers) absent at the last edition,
  • Ahmet Özdemir (20 papers) absent at the last edition,
  • Shahnaz Perveen (20 papers) absent at the last edition,
  • Sabbir Ahmed (19 papers) absent at the last edition,
  • Mehlika Dilek Altıntop (19 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in Letters in Drug Design & Discovery (based on the number of publications) are:

  • Tehran University of Medical Sciences (19 papers) published 1 paper at the last edition, 4 less than at the previous edition,
  • University of Karachi (17 papers) published 4 papers at the last edition, 1 less than at the previous edition,
  • Anadolu University (15 papers) published 3 papers at the last edition, 2 less than at the previous edition,
  • Budapest University of Technology and Economics (11 papers) absent at the last edition,
  • Chinese Academy of Sciences (9 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 15.32% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 13.33% were posted by at least one author from the top 10 institutions publishing in the journal. Another 3.81% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 14.29% of all publications and 68.57% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

    Cem Yamali;Halise Inci Gul;Tahir Cakir;Yeliz Demir

    (2020)
    39 Citations
  • Chalcones and Bis-Chalcones Analogs as DPPH and ABTS Radical Scavengers

    (2020)
    32 Citations
  • Microwave Assisted, Antimicrobial Activity and Molecular Modeling of Some Synthesized Newly Pyrimidine Derivatives Using 1, 4-diazabicyclo[2.2.2]octane as a Catalyst

    (2020)
    12 Citations
  • New Chalcone Derivatives with Pyrazole and Sulfonamide Pharmacophores as Carbonic Anhydrase Inhibitors

    Mehtap Tugrak;Halise Inci Gul;Hulya Akincioglu;Ilhami Gulcin

    (2021)
    11 Citations
  • Optimized Synthesis and Cytotoxic Activity of α-Aminophosphonates Against a Multidrug Resistant Uterine Sarcoma Cell Line

    (2022)
    9 Citations
  • Discovery of New N-hydrazinecarbothioamide Indazole Hybrids: As Potential Radical (ABTS and DPPH) Scavengers

    (2020)
    8 Citations
  • Antioxidant and ROS inhibitory activities of heterocyclic 2-Aryl-4(3H)-quinazolinone derivatives

    (2021)
    7 Citations
  • Antioxidant, Antimicrobial, and Molecular Docking Studies of Novel Chalcones and Schiff Bases Bearing 1, 4-naphthoquinone Moiety

    (2021)
    7 Citations
  • Design and Synthesis of Novel 5-Arylisoxazole-1,3,4-thiadiazole Hybrids as α-Glucosidase Inhibitors

    (2020)
    7 Citations
  • Synthesis and in vitro Biological Activity Evaluation of Novel Imidazo[2,1-b][1,3,4] thiadiazole as anti-Alzheimer agents

    Sara Azimi;Omidreza Firuzi;Aida Iraji;Afsaneh Zonouzi

    (2020)
    7 Citations

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Best Scientists Contributing to This Journal