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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
16383
World Ranking
11782
National Ranking
212

Overview

Tobias Derfuss is affiliated with the University Hospital of Basel in Switzerland and specializes primarily in medicine with a focus on neurological and immunological disorders. Their research portfolio comprises diverse subfields including pathology and forensic medicine, neurology, oncology, immunology, and molecular biology.

The scientist's work emphasizes multiple sclerosis and related neuroinflammatory conditions. The main topics covered in their research include multiple sclerosis research studies, polyomavirus and related diseases, peripheral neuropathies and disorders, cytokine signaling pathways and interactions, rheumatoid arthritis research and therapies, immunotherapy and immune responses, and neuroinflammation and neurodegeneration mechanisms.

Tobias Derfuss has published extensively in several reputable journals. The primary venues of publication include:

  • Neurology Neuroimmunology & Neuroinflammation
  • Neurology
  • Multiple Sclerosis Journal
  • JAMA Neurology
  • The Lancet Neurology

Frequent collaborators in their research include Jens Kühle, Ludwig Kappos, Heinz Wiendl, Cristina Granziera, and Pascal Benkert, indicating active participation in collaborative efforts within the neurological research community.

Among recent published papers associated with their work are:

  • Multiple sclerosis progression: time for a new mechanism-driven framework (2022, The Lancet Neurology)
  • Myelin-oligodendrocyte glycoprotein antibody-associated disease (2021, The Lancet Neurology)
  • Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis (2023, JAMA Neurology)
  • Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper) (2021, Therapeutic Advances in Neurological Disorders)
  • Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis (2022, JAMA Neurology)

Best Publications

  • Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis.

    Giulio Disanto;Christian Barro;Pascal Benkert;Yvonne Naegelin

  • ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

    X. Montalban;R. Gold;A. J. Thompson;S. Otero‐Romero

  • Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa

    Jens Kuhle;Christian Barro;Ulf Andreasson;Tobias Derfuss

  • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

    Markus Krumbholz;Diethilde Theil;Tobias Derfuss;Andreas Rosenwald

  • Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment.

    Markus Krumbholz;Diethilde Theil;Sabine Cepok;Bernhard Hemmer

  • Neurofascin as a novel target for autoantibody-mediated axonal injury

    Emily K. Mathey;Tobias Derfuss;Maria K. Storch;Kieran R. Williams

  • Myelin-oligodendrocyte glycoprotein antibody-associated disease.

    Romain Marignier;Romain Marignier;Yael Hacohen;Alvaro Cobo-Calvo;Anne Katrin Pröbstel

  • Latent Herpesvirus Infection in Human Trigeminal Ganglia Causes Chronic Immune Response

    Diethilde Theil;Tobias Derfuss;Igor Paripovic;Simone Herberger

  • Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    J. Kuhle;G. Disanto;R. Dobson;R. Adiutori

  • B cells and antibodies in multiple sclerosis pathogenesis and therapy

    Markus Krumbholz;Tobias Derfuss;Reinhard Hohlfeld;Edgar Meinl

  • Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

    A. K. Pröbstel;K. Dornmair;K. Dornmair;R. Bittner;R. Bittner;P. Sperl;P. Sperl

  • Neurofascin as a target for autoantibodies in peripheral neuropathies

    Judy King Man Ng;Joachim Malotka;Naoto Kawakami;Tobias Derfuss

  • Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

    Tobias Derfuss;Khyati Parikh;Sviataslau Velhin;Magdalena Braun

  • Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity

    Jens Kuhle;Christian Barro;Giulio Disanto;Amandine Mathias

  • Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity.

    M. Krumbholz;H. Faber;F. Steinmeyer;L. A. Hoffmann

  • Glatiramer Acetate Treatment Normalizes Deregulated microRNA Expression in Relapsing Remitting Multiple Sclerosis

    Anne Waschbisch;Monika Atiya;Ralf A. Linker;Sergej Potapov

  • Optimizing treatment success in multiple sclerosis

    Tjalf Ziemssen;Tobias Derfuss;Nicola de Stefano;Gavin Giovannoni

  • Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype.

    Anne-Katrin Pröbstel;Anne-Katrin Pröbstel;Gabrielle Rudolf;Klaus Dornmair;Nicolas Collongues

  • Prevalence of HSV-1 LAT in human trigeminal, geniculate, and vestibular ganglia and its implication for cranial nerve syndromes.

    Diethilde Theil;Viktor Arbusow;Tobias Derfuss;Michael Strupp

  • Defining distinct features of anti-MOG antibody associated central nervous system demyelination.

    Martin S. Weber;Tobias Derfuss;Imke Metz;Wolfgang Brück

Frequent Co-Authors

Ludwig Kappos
Ludwig Kappos University Hospital of Basel
Edgar Meinl
Edgar Meinl Ludwig-Maximilians-Universität München
Xavier Montalban
Xavier Montalban Autonomous University of Barcelona
Hans-Peter Hartung
Hans-Peter Hartung Heinrich Heine University Düsseldorf
Till Sprenger
Till Sprenger University Hospital of Basel
Bernhard Hemmer
Bernhard Hemmer Technical University of Munich
Tomas Olsson
Tomas Olsson Karolinska Institute
Christopher Linington
Christopher Linington University of Glasgow
Frederik Barkhof
Frederik Barkhof University College London
Frauke Zipp
Frauke Zipp Johannes Gutenberg University of Mainz

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