Ralph B. Arlinghaus

Overview

Best Publications

• BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

  Nicholas J. Donato;Ji Yuan Wu;Jonathan Stapley;Gary Gallick

  888
  Citations

• Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53

  Hiroshi Katayama;Kaori Sasai;Hidehiko Kawai;Hidehiko Kawai;Zhi Min Yuan

  802
  Citations

• Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.

  Lorri Puil;Jiaxin Liu;Gerald Gish;Geraldine Mbamalu

  625
  Citations

• Tissue-resident stem cells promote breast cancer growth and metastasis

  Fabian L. Muehlberg;Yao Hua Song;Alexander Krohn;Severin P. Pinilla

  411
  Citations

• Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl

  Gang Chen;Shyng Shiou F. Yuan;Wei Liu;Yang Xu

  350
  Citations

• AMN107, a Novel Aminopyrimidine Inhibitor of Bcr-Abl, Has In vitro Activity against Imatinib-Resistant Chronic Myeloid Leukemia

  Mirna Golemovic;Srdan Verstovsek;Francis Giles;Jorge Cortes

  281
  Citations

• Imatinib mesylate resistance through BCR-ABL independence in chronic myelogenous leukemia.

  Nicholas J. Donato;Ji Y. Wu;Jonathan Stapley;Hui Lin

  272
  Citations

• TYROSINE PHOSPHORYLATION OF CRKL IN PHILADELPHIA+ LEUKEMIA

  J ten Hoeve;RB Arlinghaus;JQ Guo;N Heisterkamp

  270
  Citations

• Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148).

  Miloslav Beran;Xiaobo Cao;Zeev Estrov;Sima Jeha

  270
  Citations

• Janus Kinase 2: A Critical Target in Chronic Myelogenous Leukemia

  Ajoy K. Samanta;Hui Lin;Tong Sun;Hagop M Kantarjian

  259
  Citations

• PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

  Paolo Neviani;Jason G. Harb;Joshua J. Oaks;Ramasamy Santhanam

  256
  Citations

• Further characterization of intracellular precursor polyproteins of Rauscher leukemia virus.

  G.A. Jamjoom;R.B. Naso;R.B. Arlinghaus

  246
  Citations

• Inhibition of Lipocalin 2 Impairs Breast Tumorigenesis and Metastasis

  Xiaohong Leng;Tian Ding;Hui Lin;Yan Wang

  238
  Citations

• Imatinib mesylate therapy for relapse after allogeneic stem cell transplantation for chronic myelogenous leukemia

  Hagop M. Kantarjian;Susan O'Brien;Jorge E. Cortes;Sergio A. Giralt

  236
  Citations

• Multiplexed volumetric bar-chart chip for point-of-care diagnostics

  Yujun Song;Yuanqing Zhang;Paul E. Bernard;James M. Reuben

  224
  Citations

• Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses

  Hagop M. Kantarjian;Jorge E. Cortes;Jorge E. Cortes;Susan O'Brien;Susan O'Brien;Francis Giles;Francis Giles

  223
  Citations

• Jak2 is involved in c-Myc induction by Bcr-Abl.

  Shanhai Xie;Hui Lin;Tong Sun;Ralph B Arlinghaus

  207
  Citations

• Biosynthesis of Rauscher leukemia viral proteins: presence of p30 and envelope p15 sequences in precursor polypeptides.

  L.J. Arcement;W.L. Karshin;R.B. Naso;G. Jamjoom

  205
  Citations

• Biosynthesis of Rauscher leukemia viral proteins

  Robert B. Naso;Larry J. Arcement;Ralph B. Arlinghaus

  198
  Citations

• Alternative splicing disrupts a nuclear localization signal in spleen tyrosine kinase that is required for invasion suppression in breast cancer.

  Lei Wang;Lindsay Duke;Peter S. Zhang;Ralph B. Arlinghaus

  194
  Citations