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Chemistry
Canada
2025

D-Index & Metrics

Chemistry

D-Index
83
Citations
25606
World Ranking
2932
National Ranking
64

Physics

D-Index
83
Citations
25410
World Ranking
2777
National Ranking
64

Research.com Recognitions

  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award
  • 2008 - Fellow of the Royal Society of Canada Academy of Science

Overview

Léon Sanche is affiliated with the Université de Sherbrooke in Canada. Their research primarily lies at the intersection of biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and pulmonary and respiratory medicine. Their work spans several subfields including surfaces, coatings and films, atomic and molecular physics and optics, and radiology, nuclear medicine and imaging.

The scientist's research topics cover a range of areas such as:

  • Radiation Therapy and Dosimetry
  • Electron and X-Ray Spectroscopy Techniques
  • DNA and Nucleic Acid Chemistry
  • Advanced Biosensing and Bioanalysis Techniques
  • Radiopharmaceutical Chemistry and Applications
  • DNA Repair Mechanisms
  • Advanced Chemical Physics Studies

Frequent publication venues where their research appears include:

  • International Journal of Molecular Sciences
  • The Journal of Physical Chemistry B
  • The Journal of Physical Chemistry Letters
  • Journal of Physics Conference Series
  • The Journal of Chemical Physics

Notable recent papers authored or co-authored by Léon Sanche include:

  • Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions, 2020, Physics in Medicine and Biology
  • Low-Energy Electron Damage to Condensed-Phase DNA and Its Constituents, 2021, International Journal of Molecular Sciences
  • Early Events in Radiobiology: Isolated and Cluster DNA Damage Induced by Initial Cations and Nonionizing Secondary Electrons, 2021, The Journal of Physical Chemistry Letters
  • Concomitant Chemoradiation Therapy with Gold Nanoparticles and Platinum Drugs Co-Encapsulated in Liposomes, 2020, International Journal of Molecular Sciences
  • High Cytotoxic Effect by Combining Copper-64 with a NOTA-Terpyridine Platinum Conjugate, 2021, Journal of Medicinal Chemistry

Léon Sanche has collaborated extensively with other researchers. Frequent co-authors include:

  • Pierre Cloutier
  • Yi Zheng
  • A. D. Bass
  • Brigitte Guérin
  • Yanfang Dong

In recognition of contributions to science, Léon Sanche was named a Fellow of the Royal Society of Canada in 2008, under the Academy of Science division.

Best Publications

  • Resonant Formation of DNA Strand Breaks by Low-Energy (3 to 20 eV) Electrons

    Badia Boudaı̈ffa;Pierre Cloutier;Darel Hunting;Michael A. Huels

  • Low energy electron-driven damage in biomolecules

    L. Sanche

  • DNA strand breaks induced by 0-4 eV electrons: the role of shape resonances.

    Frédéric Martin;Paul D. Burrow;Zhongli Cai;Pierre Cloutier

  • Single, double, and multiple double strand breaks induced in DNA by 3-100 eV electrons.

    Michael A Huels;Badia Boudaïffa;Pierre Cloutier;Darel Hunting

  • Biomolecular Damage Induced by Ionizing Radiation: The Direct and Indirect Effects of Low-Energy Electrons on DNA

    Elahe Alizadeh;Thomas M Orlando;Léon Sanche

  • Electron Transmission Spectroscopy: Rare Gases

    L. Sanche;G. J. Schulz

  • Precursors of solvated electrons in radiobiological physics and chemistry.

    Elahe Alizadeh;Léon Sanche

  • Electron transmission spectroscopy: Resonances in triatomic molecules and hydrocarbons

    L. Sanche;G. J. Schulz

  • Dissociative Electron Attachment to DNA

    X. Pan;P. Cloutier;D. Hunting;L. Sanche

  • Resonant dissociation of DNA bases by subionization electrons

    Michael A. Huels;Ina Hahndorf;Eugen Illenberger;Léon Sanche

  • Nanoscopic aspects of radiobiological damage: Fragmentation induced by secondary low-energy electrons.

    Léon Sanche

  • Radiosensitization of DNA by Gold Nanoparticles Irradiated with High-Energy Electrons

    Yi Zheng;Darel J. Hunting;Patrick Ayotte;Léon Sanche

  • Cross sections for low-energy (1-100 eV) electron elastic and inelastic scattering in amorphous ice

    M. Michaud;A. Wen;L. Sanche

  • TRANSMISSION OF 0-15 EV MONOENERGETIC ELECTRONS THROUGH THIN-FILM MOLECULAR SOLIDS

    L. Sanche

  • Density Functional Theory Studies of Electron Interaction with DNA: Can Zero eV Electrons Induce Strand Breaks?

    Xifeng Li;Michael D. Sevilla;Léon Sanche

  • Chemical basis of DNA sugar-phosphate cleavage by low-energy electrons.

    Yi Zheng;Pierre Cloutier;Darel J. Hunting;and Léon Sanche

  • Parameters governing gold nanoparticle X-ray radiosensitization of DNA in solution

    Emilie Brun;Léon Sanche;Cécile Sicard-Roselli

  • ELECTRON TRANSMISSION SPECTROSCOPY: CORE-EXCITED RESONANCES IN DIATOMIC MOLECULES.

    L. Sanche;G. J. Schulz

  • Effects of cosmic rays on atmospheric chlorofluorocarbon dissociation and ozone depletion.

    Q.-B. Lu;L. Sanche

  • Biological chemistry: Beyond radical thinking

    Léon Sanche

  • Electron stimulated desorption via dissociative attachment in amorphous H2O

    P. Rowntree;L. Parenteau;L. Sanche

Frequent Co-Authors

Eugen Illenberger
Eugen Illenberger Freie Universität Berlin
David E. Ramaker
David E. Ramaker George Washington University
Michael D. Sevilla
Michael D. Sevilla Oakland University
Denis Roy
Denis Roy Université Laval
Theodore E. Madey
Theodore E. Madey Rutgers, The State University of New Jersey
Martin Lepage
Martin Lepage Douglas Mental Health University Institute
Marcel B. Bally
Marcel B. Bally University of British Columbia
Paul-Gerhard Reinhard
Paul-Gerhard Reinhard University of Erlangen-Nuremberg
Diego Mantovani
Diego Mantovani Université Laval
Ron Naaman
Ron Naaman Weizmann Institute of Science

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