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ADMET and DMPK
H-index 10

ADMET and DMPK

1848-7718

Published by: International Association of Physical Chemists

https://pub.iapchem.org/ojs/index.php/admet/index

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 818 12 19 8

Additional Metrics

Number of Best Scientists*: 17
Documents by Best Scientists*: 24
Top 100 Ranked Scientists*: 0
SCIMAGO H-index: 23
SCIMAGO SJR: 0.664
Impact Factor: 4.3

Overview

Top Research Topics at ADMET and DMPK?

ADMET and DMPK mainly tackles studies in Solubility, Pharmacology, Chromatography, Pharmacokinetics and Drug discovery. Solubility research featured in ADMET and DMPK incorporates concerns from various other topics such as Inorganic chemistry, Henderson–Hasselbalch equation, Thermodynamics and Dissolution. Discussions in the journal are anchored in the subject of Pharmacology and the similar topic of Metabolism.

It focuses on Chromatography but the discussions also offer insight into other areas such as Lipophilicity, Permeation and Synthetic membrane. Physiologically based pharmacokinetic modelling is a major topic of Pharmacokinetics research. The Drug discovery works featured in the journal incorporate elements from In vivo, Computational biology and ADME.

The research on In vivo featured in ADMET and DMPK combines topics in other fields like Biophysics, In vitro and Distribution (pharmacology). It focused on Drug research but expanded to cover Transporter.

  • Solubility (18.72%)
  • Pharmacology (18.72%)
  • Chromatography (16.75%)

What are the most cited papers published in the journal?

  • Equilibrium solubility measurement of ionizable drugs - consensus recommendations for improving data quality (34 citations)
  • Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates (28 citations)
  • The extended clearance model and its use for the interpretation of hepatobiliary elimination data (20 citations)

Research areas of the most cited articles at ADMET and DMPK:

The journal papers tackle a plethora of topics, such as Solubility, Pharmacology, Henderson–Hasselbalch equation, Pharmacokinetics and Drug. The studies on Solubility discussed at the published papers can also contribute to research in the domains of Inorganic chemistry, Decomposition, Amorphous solid and Nuclear chemistry. While Pharmacology is the key highlight in the most cited papers, thet also covered some subjects on Drug discovery and Drug development, In vivo, Small molecule and Computational biology.

What topics the last edition of the journal is best known for?

  • Enzyme
  • Organic chemistry
  • Biochemistry

The previous edition focused in particular on these issues:

The primary areas of discussion in ADMET and DMPK are Risk analysis (engineering), Drug, Pharmacology, hERG and Embedded system. Drug development and Current (fluid) are some topics wherein Risk analysis (engineering) research discussed in ADMET and DMPK have an impact. In it, Antimicrobial and Intensive care unit, Intensive care medicine are investigated in conjunction with one another to address concerns in Drug research.

While work presented in the journal provided substantial information on Pharmacology, it also covered topics in Anticoagulant and Drug discovery. In addition to hERG, the journal tackled discussion on research areas like Torsades de pointes, Proarrhythmia, Cardiotoxicity, QT interval and In vivo. The journal held discussions to help close the divide between two different fields of study: Embedded system and Organ-on-a-chip.

The most cited articles from the last journal are:

  • Lost in modelling and simulation (1 citations)
  • Drug-like Properties and Fraction Lipophilicity Index as a combined metric (0 citations)
  • Are we ready to design oral PROTACs (0 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in ADMET and DMPK (based on the number of publications) are:

  • Kin Yip Tam (15 papers) absent at the last edition,
  • Alex Avdeef (13 papers) absent at the last edition,
  • Klára Valkó (8 papers) published 2 papers at the last edition, 1 more than at the previous edition,
  • Elisabet Fuguet (7 papers) absent at the last edition,
  • Martí Rosés (7 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in ADMET and DMPK (based on the number of publications) are:

  • University of Macau (14 papers) absent at the last edition,
  • University of Barcelona (10 papers) absent at the last edition,
  • University of Zagreb (6 papers) absent at the last edition,
  • Chongqing University of Posts and Telecommunications (5 papers) absent at the last edition,
  • University College London (5 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 54.55% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 20.00% were posted by at least one author from the top 10 institutions publishing in the journal. Another 60.00% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 0.00% of all publications and 20.00% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database

    Alex Avdeef

    (2020)
    44 Citations
  • Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode

    (2023)
    26 Citations
  • An electrochemical sensor based on a modified glassy carbon electrode for detection of epinephrine in the presence of theophylline

    (2024)
    17 Citations
  • Do you know your r2

    Alex Avdeef

    (2020)
    12 Citations
  • Challenges, current status and emerging strategies in the development of rapidly dissolving FDM 3D-printed tablets: An overview and commentary

    (2023)
    12 Citations
  • Can small drugs predict the intrinsic aqueous solubility of ‘beyond Rule of 5’ big drugs?

    Alex Avdeef;Manfred Kansy

    (2020)
    11 Citations
  • Solubility prediction in the bRo5 chemical space: where are we right now?

    Giuseppe Ermondi;Vasanthanathan Poongavanam;Maura Vallaro;Jan Kihlberg

    (2020)
    10 Citations
  • Optimization of experimental conditions for skin-PAMPA measurements

    Sara Soriano-Meseguer;Elisabet Fuguet;Adriana Port;Martí Rosés

    (2020)
    9 Citations
  • The effect of drug ionization on lipid-based formulations for the oral delivery of anti-psychotics

    Tahlia R Meola;Kara Paxton;Paul Joyce;Hayley B Schultz

    (2020)
    7 Citations
  • A simple and fast flow injection amperometry for the determination of methimazole in pharmaceutical preparations using an unmodified boron-doped diamond electrode

    (2023)
    7 Citations

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