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Medicinal Chemistry Research
H-index 18

Medicinal Chemistry Research

1054-2523

Published by: Springer

https://www.springer.com/journal/44

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 511 78 99 15

Additional Metrics

Number of Best Scientists*: 139
Documents by Best Scientists*: 160
Top 100 Ranked Scientists*: 7
SCIMAGO H-index: 64
SCIMAGO SJR: 0.47
Impact Factor: 3.1

Overview

Top Research Topics at Medicinal Chemistry Research?

The journal facilitates discussions on Stereochemistry, Pharmacology toxicology, Biochemistry, In vitro and Docking (molecular). The journal holds forums on Stereochemistry that merges themes from other disciplines such as Cell culture, Antimicrobial, Enzyme and Cytotoxicity. Medicinal Chemistry Research facilitates discussions on Antimicrobial that incorporate concepts from other fields like Antibacterial activity, Bacteria, Aspergillus niger and Candida albicans.

Antibacterial activity research presented in Medicinal Chemistry Research encompasses a variety of subjects, including Staphylococcus aureus, Bacillus subtilis and Escherichia coli. The journal focuses on Cytotoxicity research which is adjacent to topics in MTT assay. Research in Pharmacology toxicology discussed is concerned with the study of Pharmacology as a whole.

In vitro research is concerned with IC50 in particular. The Docking (molecular) works featured in Medicinal Chemistry Research incorporate elements from In silico, Molecular model and Active site. Medicinal Chemistry Research addresses concerns in the field of Quantitative structure–activity relationship by exploring it in line with topics in Pharmacophore which intersect with Virtual screening subjects.

  • Stereochemistry (44.87%)
  • Pharmacology toxicology (19.55%)
  • Biochemistry (16.83%)

What are the most cited papers published in the journal?

  • Coumarin: a potential nucleus for anti-inflammatory molecules (150 citations)
  • Thiazoles: having diverse biological activities (142 citations)
  • Benzimidazole: a medicinally important heterocyclic moiety (132 citations)

Research areas of the most cited articles at Medicinal Chemistry Research:

The most cited articles primarily tackle Stereochemistry, Organic chemistry, Antimicrobial, Pharmacology toxicology and Antibacterial activity. The works on Stereochemistry tackled in the journal papers bring together disciplines like In vitro and Cytotoxicity. While work presented in the published articles provide substantial information on Pharmacology toxicology, it also covers topics in Combinatorial chemistry and Biological activity.

What topics the last edition of the journal is best known for?

  • Enzyme
  • Organic chemistry
  • Gene

The previous edition focused in particular on these issues:

The foci of Medicinal Chemistry Research are Bioorganic chemistry, Stereochemistry, In vitro, Combinatorial chemistry and Biochemistry. Medicinal Chemistry Research explores topics in Bioorganic chemistry which can be helpful for research in disciplines like Design synthesis, Selectivity, Pharmacology toxicology and Antioxidant. Docking (molecular) is a key component of Stereochemistry research discussed in the journal.

While In vitro is the focus of it, it also provided insights into the studies of Pharmacophore, Apoptosis, In vivo and Ligand (biochemistry). Issues in Combinatorial chemistry were discussed, taking into consideration concepts from other disciplines like Biological activity, Moiety, Antibacterial activity and Carbon-13 NMR. The research on Biochemistry tackled can also make contributions to studies in the areas of Cell culture and Doxorubicin.

The most cited articles from the last journal are:

  • Pentacyclic triterpene acid conjugated with mitochondria-targeting cation F16: Synthesis and evaluation of cytotoxic activities (7 citations)
  • Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment (4 citations)
  • Synthesis and anticancer evaluation of amide derivatives of imidazo-pyridines (4 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in Medicinal Chemistry Research (based on the number of publications) are:

  • Taibi Ben Hadda (32 papers) absent at the last edition,
  • Nisheeth C. Desai (27 papers) absent at the last edition,
  • Balasubramanian Narasimhan (20 papers) absent at the last edition,
  • Najma Sultana (19 papers) absent at the last edition,
  • Khalid Mohammed Khan (19 papers) published 1 paper at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in Medicinal Chemistry Research (based on the number of publications) are:

  • Central Drug Research Institute (73 papers) published 2 papers at the last edition,
  • University of Karachi (71 papers) published 5 papers at the last edition, 4 more than at the previous edition,
  • Indian Institute of Chemical Technology (70 papers) absent at the last edition,
  • Cairo University (60 papers) published 3 papers at the last edition, 2 more than at the previous edition,
  • King Saud University (56 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 2.44% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 10.62% were posted by at least one author from the top 10 institutions publishing in the journal. Another 10.00% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 10.00% of all publications and 69.38% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Antimicrobial activity of quaternary ammonium salts: structure-activity relationship

    (2022)
    99 Citations
  • Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment

    (2020)
    72 Citations
  • Isatin derivatives as broad-spectrum antiviral agents: the current landscape

    (2022)
    50 Citations
  • The pyridazine heterocycle in molecular recognition and drug discovery

    (2023)
    31 Citations
  • New synthetic 1H-1,2,3-triazole derivatives of 3-O-acetyl-β-boswellic acid and 3-O-acetyl-11-keto-β-boswellic acid from Boswellia sacra inhibit carbonic anhydrase II in vitro

    (2020)
    28 Citations
  • α-Glucosidase and α-amylase inhibition, molecular modeling and pharmacokinetic studies of new quinazolinone-1,2,3-triazole-acetamide derivatives

    Ali Yavari;Maryam Mohammadi-Khanaposhtani;Shahram Moradi;Saeed Bahadorikhalili

    (2021)
    25 Citations
  • Different barbiturate derivatives linked to aryl hydrazone moieties as urease inhibitors; design, synthesis, urease inhibitory evaluations, and molecular dynamic simulations

    (2023)
    24 Citations
  • Design, synthesis, and biological evaluation of 1-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-3-phenylurea derivatives as anticancer agents

    Ayoub Aghcheli;Mahsa Toolabi;Adileh Ayati;Setareh Moghimi

    (2020)
    23 Citations
  • Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors

    (2023)
    22 Citations
  • Thiazole-based and thiazolidine-based protein tyrosine phosphatase 1B inhibitors as potential anti-diabetes agents

    (2020)
    20 Citations

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Best Scientists Contributing to This Journal