Cellular Signalling

Top Research Topics at Cellular Signalling?

The primary areas of discussion in Cellular Signalling are Cell biology, Signal transduction, Molecular biology, Biochemistry and Cancer research. The close relationship between Receptor and Endocrinology is one of the points of interest dissected in Cell biology research. The in-depth study on Signal transduction also explores topics in the intersecting field of Transcription factor.

It explores issues in Molecular biology which can be linked to other research areas like Cell culture, Protein kinase C and Protein kinase A. The Biochemistry works, particularly on G protein are tackled in the journal. The journal focuses on Cancer research but the discussions also offer insight into other areas such as Cell growth, Apoptosis, Gene knockdown, Cancer cell and Downregulation and upregulation.

More specifically, the research on Phosphorylation in the journal is related to Tyrosine phosphorylation. Cellular Signalling is mostly focused on MAPK/ERK pathway, specifically p38 mitogen-activated protein kinases. Most of the works presented in Cellular Signalling deals with Protein kinase B but it intersects with the subject of PI3K/AKT/mTOR pathway.

• Cell biology (53.84%)
• Signal transduction (25.83%)
• Molecular biology (19.19%)

What are the most cited papers published in the journal?

• Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling (2400 citations)
• LPS induction of gene expression in human monocytes (1985 citations)
• The protein kinase B/Akt signalling pathway in human malignancy. (1397 citations)

Research areas of the most cited articles at Cellular Signalling:

The journal papers focus largely on the fields of Cell biology, Signal transduction, Biochemistry, Cancer research and Molecular biology. The most cited papers tackle studies in Receptor and the interrelated subject of Endocrinology to gain insights into Cell biology. The journal publications hold forums on Signal transduction that merge themes from other disciplines such as Transcription factor and Protein kinase A.

What topics the last edition of the journal is best known for?

• Gene
• Enzyme
• Internal medicine

The previous edition focused in particular on these issues:

The concepts of Cell biology, Cancer research, Signal transduction, Apoptosis and Downregulation and upregulation are tackled in Cellular Signalling. Cellular Signalling dives deep in exploring the relationship between the study of Cell biology and Autophagy. Some problems in Cancer research that were presented in the journal overlapped with concepts under Cancer, Metastasis, Cell growth, Gene knockdown and microRNA.

The concepts on Cell growth presented in Cellular Signalling can also apply to other research fields, including Carcinogenesis, Cell cycle and Gene silencing. Research in Receptor and the interrelating topic of Neuroscience were among the subjects of interest in the Signal transduction studies discussed in Cellular Signalling. Cellular Signalling explores issues in Apoptosis which can be linked to other research areas like Oxidative stress, Cell, Reactive oxygen species and Pharmacology.

The most cited articles from the last journal are:

• Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer. (16 citations)
• Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators. (14 citations)
• Biased agonism at the cannabinoid receptors - Evidence from synthetic cannabinoid receptor agonists. (9 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Cellular Signalling (based on the number of publications) are:

• Chuen-Mao Yang (27 papers) absent at the last edition,
• Terence E. Hébert (25 papers) published 1 paper at the last edition,
• Nigel J. Pyne (24 papers) published 1 paper at the last edition the same number as at the previous edition,
• Sung Ho Ryu (23 papers) absent at the last edition,
• Miles D. Houslay (23 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Cellular Signalling (based on the number of publications) are:

• French Institute of Health and Medical Research (127 papers) published 1 paper at the last edition the same number as at the previous edition,
• National Institutes of Health (116 papers) published 1 paper at the last edition, 5 less than at the previous edition,
• University of Glasgow (97 papers) published 2 papers at the last edition, 6 less than at the previous edition,
• Shanghai Jiao Tong University (60 papers) published 5 papers at the last edition, 5 less than at the previous edition,
• McGill University (54 papers) published 2 papers at the last edition, 1 more than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 4.51% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 9.45% were posted by at least one author from the top 10 institutions publishing in the journal. Another 3.94% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 13.78% of all publications and 72.83% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.