Alexandre P. Zavascki

Best Publications

• Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review

  Alexandre Prehn Zavascki;Alexandre Prehn Zavascki;Luciano Zubaran Goldani;Jian Li;Roger L. Nation

  1031
  Citations

• International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).

  Brian T. Tsuji;Jason M. Pogue;Alexandre P. Zavascki;Mical Paul;Mical Paul

  938
  Citations

• Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy

  Alexandre P Zavascki;Cecília G Carvalhaes;Renata C Picão;Ana C Gales

  547
  Citations

• Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens

  Ana M Sandri;Cornelia Barbara Landersdorfer;Cornelia Barbara Landersdorfer;Jovan Jacob;Marcio M Boniatti

  470
  Citations

• Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients

  Alexandre P. Zavascki;Luciano Z. Goldani;Guoying Cao;Silvana V. Superti

  267
  Citations

• Nephrotoxicity of Polymyxins: Is There Any Difference between Colistimethate and Polymyxin B?

  Alexandre P Zavascki;Roger L Nation

  217
  Citations

• Combination therapy for carbapenem-resistant Gram-negative bacteria

  Unknown

  192
  Citations

• Risk factors for acute kidney injury in patients treated with polymyxin B or colistin methanesulfonate sodium.

  Unknown

  174
  Citations

• The influence of metallo-β-lactamase production on mortality in nosocomial Pseudomonas aeruginosa infections

  Unknown

  160
  Citations

• The impact of polymyxin B dosage on in-hospital mortality of patients treated with this antibiotic

  Unknown

  151
  Citations

• Multicenter Prospective Cohort Study of Renal Failure in Patients Treated with Colistin versus Polymyxin B

  Unknown

  149
  Citations

• Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA.

  Unknown

  146
  Citations

• Outbreak of carbapenem-resistant Pseudomonas aeruginosa producing SPM-1 metallo-β-lactamase in a teaching hospital in southern Brazil

  Unknown

  139
  Citations

• Risk factors for acute kidney injury (AKI) in patients treated with polymyxin B and influence of AKI on mortality: a multicentre prospective cohort study

  Unknown

  135
  Citations

• Risk factors for imipenem-resistant Pseudomonas aeruginosa: a comparative analysis of two case-control studies in hospitalized patients.

  Unknown

  125
  Citations

• Polymyxin Acute Kidney Injury: Dosing and Other Strategies to Reduce Toxicity.

  Roger L. Nation;Maria Helena da Silva Pitombeira Rigatto;Diego Rodrigues Falci;Alexandre Prehn Zavascki

  120
  Citations

• Reappraisal of Pseudomonas aeruginosa hospital-acquired pneumonia mortality in the era of metallo-β-lactamase-mediated multidrug resistance: a prospective observational study

  Unknown

  107
  Citations

• Characterization of Tn3000, a transposon responsible for blaNDM-1 dissemination among Enterobacteriaceae in Brazil, Nepal, Morocco, and India

  Juliana Coutinho Campos;Maria José Félix da Silva;Paulo Roberto Nascimento dos Santos;Elaine Menezes Barros

  106
  Citations

• Polymyxin B in Combination with Antimicrobials Lacking In Vitro Activity versus Polymyxin B in Monotherapy in Critically Ill Patients with Acinetobacter baumannii or Pseudomonas aeruginosa Infections

  Unknown

  93
  Citations

• Pharmacokinetics of polymyxin B in patients on continuous venovenous haemodialysis

  Ana M Sandri;Cornelia Barbara Landersdorfer;Cornelia Barbara Landersdorfer;Jovan Jacob;Marcio M Boniatti

  92
  Citations