Epigenetics

Top Research Topics at Epigenetics?

The journal primarily tackles DNA methylation, Epigenetics, Genetics, Methylation and Molecular biology. The concepts on DNA methylation presented in it can also apply to other research fields, including Regulation of gene expression and Cancer research. The studies in Cancer research featured incorporate elements of Cancer cell, Cancer, Carcinogenesis, microRNA and Gene silencing.

While Epigenetics mainly focused on Epigenetics studies, it also tackled the scientific discipline of interrelated fields such as

• Histone together with Acetylation,
• Endocrinology together with Pregnancy.. Chromatin, Genomic imprinting, RNA-Directed DNA Methylation, Histone methylation and Genome are all aspects of Genetics discussed in Epigenetics. The close relationship between Histone code and Histone methyltransferase and Histone H1 is one of the points of interest dissected in Histone methylation research.

The tackled Methylation research is interrelated with Bisulfite sequencing which concerns subjects like Illumina Methylation Assay. Gene expression is a primary topic of Gene research in the journal. Most of the works presented in Epigenetics deals with CpG site but it intersects with the subject of Human genome.

• DNA methylation (63.68%)
• Epigenetics (52.78%)
• Genetics (35.91%)

What are the most cited papers published in the journal?

• Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses (1119 citations)
• Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray (979 citations)
• Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. (789 citations)

Research areas of the most cited articles at Epigenetics:

The published papers investigate studies in DNA methylation, Epigenetics, Genetics, Methylation and Molecular biology. While work presented in the most cited papers provide substantial information on DNA methylation, it also covers topics in Endocrinology and Cancer research. The studies on Epigenetics discussed at the journal articles can also contribute to research in the domains of Bioinformatics, Regulation of gene expression, microRNA, Epigenesis and Epigenome.

What topics the last edition of the journal is best known for?

• Gene
• Cancer
• DNA

The previous edition focused in particular on these issues:

Epigenetics covers a variety of subjects, including DNA methylation, Epigenetics, Methylation, Gene and Cell biology. It features research on DNA methylation in an attempt to reinforce studies in the field of Genetics. It deals with Epigenetics in conjunction with Cancer research and similar fields in Carcinogenesis, Downregulation and upregulation and Breast cancer.

While the journal focused on Methylation, it was also able to explore topics like Cell-free fetal DNA, Molecular biology, Biomarker (medicine) and Pregnancy. While it focused on Cell biology, it was also able to explore topics like Acetylation, Transcription factor, Chromatin, Histone and Transcription (biology). The journal focuses on Chromatin but the discussions also offer insight into other areas such as Enhancer, Epigenomics and Regulation of gene expression.

The most cited articles from the last journal are:

• Epigenetic mechanisms regulating COVID-19 infection. (33 citations)
• Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing. (13 citations)
• Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of 'epidrugs'. (9 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Epigenetics (based on the number of publications) are:

• Carmen J. Marsit (33 papers) published 4 papers at the last edition, 1 more than at the previous edition,
• Andrea A. Baccarelli (32 papers) published 4 papers at the last edition, 2 more than at the previous edition,
• Manel Esteller (30 papers) published 1 paper at the last edition, 1 less than at the previous edition,
• Karl T. Kelsey (21 papers) published 3 papers at the last edition,
• Brock C. Christensen (20 papers) published 2 papers at the last edition, 1 less than at the previous edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Epigenetics (based on the number of publications) are:

• Harvard University (70 papers) published 3 papers at the last edition, 1 less than at the previous edition,
• Columbia University (44 papers) published 7 papers at the last edition, 4 more than at the previous edition,
• University of Michigan (44 papers) published 7 papers at the last edition,
• Icahn School of Medicine at Mount Sinai (43 papers) published 5 papers at the last edition, 1 more than at the previous edition,
• National Institutes of Health (41 papers) published 4 papers at the last edition, 2 less than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 1.37% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 21.53% were posted by at least one author from the top 10 institutions publishing in the journal. Another 6.25% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 21.53% of all publications and 50.69% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.