Gérard Le Fur

Overview

Best Publications

• SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

  Murielle Rinaldi-Carmona;Francis Barth;Michel Héaulme;David Shire

  2697
  Citations

• Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations.

  Sylvaine Galiègue;Sophie Mary;Jean Marchand;Danielle Dussossoy

  2459
  Citations

• A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1 EVIDENCE FOR A NEW MODEL OF RECEPTOR/LIGAND INTERACTIONS

  Monsif Bouaboula;Sylvie Perrachon;Laura Milligan;Xavier Canat

  699
  Citations

• In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist

  Xavier Emonds-Alt;Jean-Daniel Doutremepuich;Michel Heaulme;Gervais Neliat

  551
  Citations

• Cannabinoid‐receptor expression in human leukocytes

  Monsif Bouaboula;Murielle Rinaldi;Pierre Carayon;Christine Carillon

  504
  Citations

• The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance

  Omar Jbilo;Christine Ravinet-Trillou;Michèle Arnone;Isabelle Buisson

  498
  Citations

• An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing.

  David Shire;Christine Carillon;Mourad Kaghad;Bernard Calandra

  479
  Citations

• Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats.

  Magali Gary-Bobo;Ghizlane Elachouri;Jean François Gallas;Philip Janiak

  424
  Citations

• Blockade of CRF 1 or V 1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

  R Alonso;G Griebel;G Pavone;J Stemmelin

  412
  Citations

• Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression.

  Monsif Bouaboula;Caroline Poinot-Chazel;Jean Marchand;Xavier Canat

  402
  Citations

• Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist.

  Murielle Rinaldi-Carmona;Francis Barth;Michel Héaulme;Richard Alonso

  400
  Citations

• Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors

  Natalio Vita;Patrick Laurent;Sylvie Lefort;Pascale Chalon

  386
  Citations

• Anandamide induced PPARγ transcriptional activation and 3T3-L1 preadipocyte differentiation

  Monsif Bouaboula;Sandrine Hilairet;Jean Marchand;Lluis Fajas

  337
  Citations

• Molecular cloning of a levocabastine-sensitive neurotensin binding site

  Pascale Chalon;Natalio Vita;Mourad Kaghad;Marie Guillemot

  326
  Citations

• Characterization of (2S,4R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist

  Claudine Serradeil-Le Gal;Jean Wagnon;Jacques Simiand;Guy Griebel

  320
  Citations

• Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor

  David Shire;Bernard Calandra;Murielle Rinaldi-Carmona;Didier Oustric

  282
  Citations

• Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716.

  Sandrine Hilairet;Monsif Bouaboula;Dominique Carrière;Gérard Le Fur

  264
  Citations

• Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells.

  Monsif Bouaboula;Bernard Bourrié;Murielle Rinaldi-Carmona;David Shire

  256
  Citations

• The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes.

  Magali Gary-Bobo;Ghizlane Elachouri;Bernard Scatton;Gérard Le Fur

  229
  Citations

• Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis

  Vincent Santucci;Jean Jacques Storme;Philippe Soubrie;Gerard Le Fur

  229
  Citations