D-Index & Metrics Best Publications
Biology and Biochemistry
Switzerland
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 86 Citations 26,484 184 World Ranking 1904 National Ranking 47

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Genetics, Gene, Allele, Molecular biology and Drug metabolism are his primary areas of study. His study in the field of Arylamine N-acetyltransferase, Locus, Point mutation and Exon also crosses realms of Pseudogene. His Allele research is multidisciplinary, incorporating elements of Mephenytoin, CYP2C19, Phenotype, Genotyping and Genetic variation.

He has included themes like Mutant and Restriction fragment length polymorphism in his Molecular biology study. His research integrates issues of Cytochrome, Xenobiotic and Cytochrome P450 in his study of Drug metabolism. His study focuses on the intersection of Cytochrome and fields such as Antibody with connections in the field of Microsome.

His most cited work include:

  • The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. (841 citations)
  • IDENTIFICATION OF A NEW GENETIC DEFECT RESPONSIBLE FOR THE POLYMORPHISM OF (S)-MEPHENYTOIN METABOLISM IN JAPANESE (700 citations)
  • Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. (619 citations)

What are the main themes of his work throughout his whole career to date?

Urs A. Meyer spends much of his time researching Biochemistry, Genetics, Cytochrome P450, Gene and Molecular biology. He interconnects Isozyme and Pharmacology in the investigation of issues within Cytochrome P450. His Locus, Gene expression, Exon and Point mutation study, which is part of a larger body of work in Gene, is frequently linked to Pseudogene, bridging the gap between disciplines.

Urs A. Meyer combines subjects such as Complementary DNA, Nucleic acid sequence, Peptide sequence and Restriction enzyme with his study of Molecular biology. His Microsome study integrates concerns from other disciplines, such as Hydroxylation, Bufuralol, Sparteine, Stereochemistry and Cytochrome. His Allele study combines topics in areas such as CYP2D6, Genotyping and Genetic variation.

He most often published in these fields:

  • Biochemistry (38.46%)
  • Genetics (23.08%)
  • Cytochrome P450 (27.47%)

What were the highlights of his more recent work (between 2002-2021)?

  • Biochemistry (38.46%)
  • Pregnane X receptor (12.64%)
  • Constitutive androstane receptor (10.99%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Biochemistry, Pregnane X receptor, Constitutive androstane receptor, Nuclear receptor and Pharmacology. His Constitutive androstane receptor research incorporates themes from Retinoid X receptor, Drug metabolism, Xenobiotic and Receptor, Internal medicine. His study in Nuclear receptor is interdisciplinary in nature, drawing from both AMP-activated protein kinase, Signal transduction, Protein kinase A and Transactivation.

His studies deal with areas such as Toxicology, Computational biology, Toxicity and In vivo as well as Pharmacology. His studies in Cytochrome P450 integrate themes in fields like Molecular biology and Heme. In his study, which falls under the umbrella issue of Pharmacogenetics, Genetics is strongly linked to Therapeutic failure.

Between 2002 and 2021, his most popular works were:

  • Induction of Drug Metabolism: The Role of Nuclear Receptors (381 citations)
  • Pharmacogenetics: five decades of therapeutic lessons from genetic diversity (313 citations)
  • Nutritional Regulation of Hepatic Heme Biosynthesis and Porphyria through PGC-1α (273 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Urs A. Meyer mostly deals with Biochemistry, Pregnane X receptor, Constitutive androstane receptor, Nuclear receptor and Cytochrome P450. His Pregnane X receptor research incorporates elements of Farnesoid X receptor, Retinoid X receptor, Drug metabolism and Transactivation. His research integrates issues of Liver X receptor, Liver X receptor alpha, Xenobiotic and Liver X receptor beta in his study of Retinoid X receptor.

His research in Transactivation intersects with topics in Pharmacology and In vivo. His Nuclear receptor study combines topics from a wide range of disciplines, such as AMP-activated protein kinase, AMPK, Protein kinase A, Receptor and Signal transduction. His work carried out in the field of Cytochrome P450 brings together such families of science as ALAS1, Hemeprotein, Heme and Enzyme inducer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans.

S. M. F. De Morais;G. R. Wilkinson;J. Blaisdell;K. Nakamura.
Journal of Biological Chemistry (1994)

1280 Citations

IDENTIFICATION OF A NEW GENETIC DEFECT RESPONSIBLE FOR THE POLYMORPHISM OF (S)-MEPHENYTOIN METABOLISM IN JAPANESE

S. M. F. De Morais;G. R. Wilkinson;J. Blaisdell;U. A. Meyer.
Molecular Pharmacology (1994)

997 Citations

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

F J Gonzalez;R C Skoda;S Kimura;M Umeno.
Nature (1988)

897 Citations

Pharmacogenetics and adverse drug reactions

Urs A Meyer.
The Lancet (2000)

769 Citations

Molecular mechanisms of genetic polymorphisms of drug metabolism.

Urs A. Meyer;Ulrich M. Zanger.
Annual Review of Pharmacology and Toxicology (1997)

726 Citations

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

T Kronbach;D Mathys;M Umeno;F J Gonzalez.
Molecular Pharmacology (1989)

699 Citations

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification.

M Heim;U.A Meyer.
The Lancet (1990)

607 Citations

Induction of Drug Metabolism: The Role of Nuclear Receptors

Christoph Handschin;Urs A. Meyer.
Pharmacological Reviews (2003)

604 Citations

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

M. Blum;D.M. Grant;W. McBRIDE;M. Heim.
DNA and Cell Biology (1990)

594 Citations

Nomenclature for human CYP2D6 alleles.

A K Daly;J Brockmoller;F Broly;M Eichelbaum.
Pharmacogenetics (1996)

583 Citations

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