His primary areas of investigation include Cell biology, Molecular biology, Immunology, Histamine and Endocrinology. His Cell biology study combines topics in areas such as Apoptosis, Cytotoxic T cell, Psoriasis and B-1 cell. His Molecular biology research includes elements of Tyrosine kinase, Signal transduction, Antigen, Immunoglobulin light chain and Stem cell.
His Immunology research is multidisciplinary, incorporating perspectives in In vivo and Lymph. Takeshi Watanabe has researched Histamine in several fields, including Histamine receptor, Histamine H2 receptor, Pathogenesis and Histamine H1 receptor. His Endocrinology research is multidisciplinary, incorporating elements of Biological activity, Internal medicine, Biochemistry and Almorexant.
His primary scientific interests are in Molecular biology, Immunology, Internal medicine, Antigen and Endocrinology. His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Immunoglobulin light chain, Antibody, Monoclonal antibody and Gene. His work carried out in the field of Immunology brings together such families of science as In vivo and Cell biology.
His Antigen research is multidisciplinary, relying on both Immunohistochemistry and Pathology. His studies link Histamine H1 receptor with Endocrinology. His research in Histamine intersects with topics in Histamine receptor, Histidine decarboxylase and Histamine H4 receptor, Histamine H2 receptor.
The scientist’s investigation covers issues in Immunology, Cell biology, Stromal cell, Spleen and Regeneration. His Immunology study integrates concerns from other disciplines, such as Cytotoxic T cell, In vivo and Histamine. Takeshi Watanabe is researching Histamine as part of the investigation of Internal medicine and Endocrinology.
His work deals with themes such as Cell, Chemotaxis, Transgene and B cell, which intersect with Cell biology. Takeshi Watanabe interconnects Lymphatic system and Immune system, Lymphotoxin in the investigation of issues within Stromal cell. His research investigates the connection with Histamine H4 receptor and areas like Apolipoprotein E which intersect with concerns in Molecular biology, Histidine decarboxylase and Histamine receptor.
Takeshi Watanabe spends much of his time researching Immunology, Cell biology, Antigen, BCL6 and IL-2 receptor. His studies in Immunology integrate themes in fields like Phenotype, Cytotoxic T cell and Stem cell. His research integrates issues of T cell, Lymphocyte homeostasis and B cell in his study of Cell biology.
His Antigen research incorporates themes from Lymph, Immune homeostasis, Endogeny, Basophil and In vivo. His BCL6 research also works with subjects such as
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Complete sequencing and characterization of 21,243 full-length human cDNAs
Toshio Ota;Yutaka Suzuki;Tetsuo Nishikawa;Tetsuji Otsuki.
Nature Genetics (2004)
Mouse-human chimaeric immunoglobulin heavy chain, and chimaeric DNA encoding it
Akira Kudo;Yushi Nishimura;Yataro Ichikawa;Takeshi Watanabe.
Arousal effect of orexin A depends on activation of the histaminergic system
Zhi-Li Huang;Wei-Min Qu;Wei-Dong Li;Takatoshi Mochizuki.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors
Marek Jutel;Takeshi Watanabe;Sven Klunker;Mübeccel Akdis.
Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26
Didier Marguet;Laurie Baggio;Takashi Kobayashi;Anne-Marie Bernard.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
Hirofumi Nishizumi;Ichiro Taniuchi;Yuji Yamanashi;Daisuke Kitamura.
HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.
Yasuhiro Suzuki;Corinne Demoliere;Daisuke Kitamura;Hiromichi Takeshita.
Journal of Immunology (1997)
Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors
Isao Inoue;Kazuhiko Yanai;Daisuke Kitamura;Ichiro Taniuchi.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1.
Manabu Nakashima;Kenzo Sonoda;Takeshi Watanabe.
Nature Medicine (1999)
Immune regulation by histamine
Marek Jutel;Takeshi Watanabe;Mübeccel Akdis;Kurt Blaser.
Current Opinion in Immunology (2002)
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