D-Index & Metrics Best Publications
Taira Maekawa

Taira Maekawa

Kyoto University
Japan

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Cancer research, Cell growth, Immunology, Imatinib mesylate and ABL are his primary areas of study. His Cancer research research includes themes of Cell culture, Tyrosine kinase, Chronic myelogenous leukemia, Leukemia and In vivo. His research integrates issues of Transfection, Small interfering RNA, Apoptosis, Programmed cell death and Myeloid leukemia in his study of Cell growth.

His study looks at the relationship between Immunology and fields such as Lung cancer, as well as how they intersect with chemical problems. His research in Imatinib mesylate tackles topics such as Tyrosine-kinase inhibitor which are related to areas like Proteasome inhibitor, BH3 Mimetic ABT-737, Inhibitor of apoptosis domain, Bcl-2 family and Intrinsic apoptosis. In his work, Philadelphia chromosome and LYN is strongly intertwined with Imatinib, which is a subfield of ABL.

His most cited work include:

  • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis (260 citations)
  • NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia. (210 citations)
  • Insulin independence after living-donor distal pancreatectomy and islet allotransplantation (193 citations)

What are the main themes of his work throughout his whole career to date?

Taira Maekawa mainly focuses on Cancer research, Immunology, Bone marrow, Stem cell and Molecular biology. His Cancer research research is multidisciplinary, incorporating elements of Leukemia, ABL and Cell growth. His Leukemia research integrates issues from Myeloid leukemia and Pharmacology.

Taira Maekawa has included themes like Apoptosis, Cell culture and In vivo in his Cell growth study. His studies deal with areas such as Progenitor cell and Internal medicine, Transplantation as well as Immunology. His Stem cell research is multidisciplinary, incorporating perspectives in Stromal cell and Mesenchymal stem cell.

He most often published in these fields:

  • Cancer research (30.88%)
  • Immunology (29.41%)
  • Bone marrow (17.89%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (29.41%)
  • Cancer research (30.88%)
  • Stem cell (15.93%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immunology, Cancer research, Stem cell, Haematopoiesis and Bone marrow. His studies in Immunology integrate themes in fields like Internal medicine, Cellular differentiation and Genotype. His biological study spans a wide range of topics, including Cell cycle, Leukemia, Protein kinase B and ABL.

The study incorporates disciplines such as Stromal cell, Stem cell transplantation for articular cartilage repair, Andrology, Mesenchymal stem cell and Transplantation in addition to Stem cell. His research in Haematopoiesis intersects with topics in Progenitor cell, Molecular biology, Ccaat-enhancer-binding proteins and Myeloid. His work carried out in the field of Molecular biology brings together such families of science as Apoptosis and Cell culture.

Between 2012 and 2021, his most popular works were:

  • Myeloid-Derived Suppressor Cells Play Crucial Roles in the Regulation of Mouse Collagen-Induced Arthritis (107 citations)
  • Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population (90 citations)
  • A Clinical, Pathological, and Genetic Characterization of Methotrexate-associated Lymphoproliferative Disorders (68 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

Taira Maekawa focuses on Cancer research, Immunology, Bone marrow, Stem cell and Haematopoiesis. His Cancer research study combines topics in areas such as Protein kinase B, ABL, Cell cycle, Leukemia and Colorectal cancer. His ABL study which covers Ponatinib that intersects with Imatinib mesylate and Chronic myelogenous leukemia.

His Immunology research incorporates elements of Chromosome 17, Cellular differentiation and Genotype. As a part of the same scientific family, Taira Maekawa mostly works in the field of Stem cell, focusing on Mesenchymal stem cell and, on occasion, Stromal cell, Transplantation, Cell therapy, Regulatory T cell and IL-2 receptor. Taira Maekawa combines subjects such as Myeloid, CD34 and CEBPB with his study of Haematopoiesis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.

Shinya Kimura;Haruna Naito;Hidekazu Segawa;Junya Kuroda.
Blood (2005)

332 Citations

Insulin independence after living-donor distal pancreatectomy and islet allotransplantation

Shinichi Matsumoto;Teru Okitsu;Yasuhiro Iwanaga;Hirofumi Noguchi.
The Lancet (2005)

295 Citations

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer

Masaki Nogawa;Takeshi Yuasa;Shinya Kimura;Motoyoshi Tanaka.
Journal of Clinical Investigation (2005)

269 Citations

Targeting the Wnt/β-catenin signaling pathway in human cancers.

Hisayuki Yao;Eishi Ashihara;Eishi Ashihara;Taira Maekawa.
Expert Opinion on Therapeutic Targets (2011)

215 Citations

Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy

Kiyoshi Sato;Shinya Kimura;Hidekazu Segawa;Asumi Yokota.
International Journal of Cancer (2005)

198 Citations

Successful islet transplantation from nonheartbeating donor pancreata using modified Ricordi islet isolation method.

Shinichi Matsumoto;Teru Okitsu;Yasuhiro Iwanaga;Hirofumi Noguchi.
Transplantation (2006)

194 Citations

Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines.

Seiji Matsumoto;Shinya Kimura;Hidekazu Segawa;Junya Kuroda.
Lung Cancer (2005)

179 Citations

Myeloid-Derived Suppressor Cells Play Crucial Roles in the Regulation of Mouse Collagen-Induced Arthritis

Wataru Fujii;Eishi Ashihara;Eishi Ashihara;Hideyo Hirai;Hidetake Nagahara.
Journal of Immunology (2013)

175 Citations

Progressive graft fibrosis and donor-specific human leukocyte antigen antibodies in pediatric late liver allografts.

Aya Miyagawa-Hayashino;Atushi Yoshizawa;Yoichiro Uchida;Hiroto Egawa.
Liver Transplantation (2012)

168 Citations

The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate

Junya Kuroda;Shinya Kimura;Hidekazu Segawa;Yutaka Kobayashi.
Blood (2003)

168 Citations

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