H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 63 Citations 13,125 153 World Ranking 1512 National Ranking 52
Medicine D-index 70 Citations 16,501 189 World Ranking 16150 National Ranking 537

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Immune system
  • Cytokine

T. van der Poll focuses on Internal medicine, Endocrinology, Tumor necrosis factor alpha, Cytokine and Immunology. In general Endocrinology study, his work on Inflammatory reflex, Acetylcholine and Vagus nerve often relates to the realm of GTS-21, thereby connecting several areas of interest. His Tumor necrosis factor alpha study integrates concerns from other disciplines, such as Pentoxifylline, Fibrinolysis, Coagulation and Bolus.

T. van der Poll interconnects Hormone and Stimulation in the investigation of issues within Cytokine. His studies in Immunology integrate themes in fields like Disseminated intravascular coagulation and Tuberculosis. His research integrates issues of Innate immune system, Pathogenesis and Endothelial dysfunction in his study of Sepsis.

His most cited work include:

  • Activation of coagulation after administration of tumor necrosis factor to normal subjects. (610 citations)
  • Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees (369 citations)
  • Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees. (330 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immunology, Internal medicine, Sepsis, Cytokine and Tumor necrosis factor alpha. T. van der Poll combines subjects such as Fibrinolysis, Coagulation and Pharmacology with his study of Immunology. The study incorporates disciplines such as Gastroenterology, Endocrinology and Surgery in addition to Internal medicine.

His Sepsis research is multidisciplinary, incorporating elements of Streptococcus pneumoniae, Pathogenesis, Pneumonia, Burkholderia pseudomallei and Intensive care medicine. The concepts of his Cytokine study are interwoven with issues in Stimulation, Pathophysiology and Tuberculosis. His Tumor necrosis factor alpha research incorporates elements of Neutrophil degranulation, Neutrophilia, Antibody, Monoclonal antibody and Receptor antagonist.

He most often published in these fields:

  • Immunology (51.80%)
  • Internal medicine (31.53%)
  • Sepsis (23.42%)

What were the highlights of his more recent work (between 2014-2021)?

  • Immunology (51.80%)
  • Sepsis (23.42%)
  • Internal medicine (31.53%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Sepsis, Internal medicine, Intensive care medicine and In patient. His work investigates the relationship between Immunology and topics such as Coagulation that intersect with problems in Hemostasis. His Sepsis research is multidisciplinary, incorporating perspectives in Platelet activation, Endothelium and Intensive care unit.

With his scientific publications, his incorporates both Internal medicine and Canakinumab. He works mostly in the field of Intensive care medicine, limiting it down to topics relating to Antibiotic resistance and, in certain cases, Organ dysfunction, Sequential organ failure assessment and Etiology, as a part of the same area of interest. He studied Fibrinolysis and Meningitis that intersect with Inflammation.

Between 2014 and 2021, his most popular works were:

  • Endothelial barrier dysfunction in septic shock (154 citations)
  • Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis (98 citations)
  • Platelet and endothelial cell P‐selectin are required for host defense against Klebsiella pneumoniae‐induced pneumosepsis (26 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Immune system
  • Inflammation

T. van der Poll mostly deals with Immunology, Sepsis, Platelet, Internal medicine and Thrombin. His work in Immunology tackles topics such as Coagulation which are related to areas like Hemostasis. While the research belongs to areas of Sepsis, he spends his time largely on the problem of Endothelium, intersecting his research to questions surrounding Endothelial stem cell, Cytokine, P-selectin and Bone marrow.

His biological study spans a wide range of topics, including Fibrinogen, Pharmacology, Neutrophil extracellular traps and Fibrin. The Internal medicine study combines topics in areas such as Pediatrics and Pathology. His Thrombin study deals with Fibrinolysis intersecting with Placebo, Venous blood, Prednisolone and Gastroenterology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Activation of coagulation after administration of tumor necrosis factor to normal subjects.

T. van der Poll;H. R. Büller;H. ten Cate;C. H. Wortel.
The New England Journal of Medicine (1990)

807 Citations

Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees

M Levi;H ten Cate;K A Bauer;T van der Poll.
Journal of Clinical Investigation (1994)

505 Citations

Pathogenesis of disseminated intravascular coagulation in sepsis

M. Levi;H. Ten Cate;T. Van Der Poll;S. J. H. Van Deventer.
JAMA (1993)

487 Citations

Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.

T van der Poll;M Levi;C E Hack;H ten Cate.
Journal of Experimental Medicine (1994)

467 Citations

Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.

D. Pajkrt;J. E. Doran;F. Koster;P. G. Lerch.
Journal of Experimental Medicine (1996)

457 Citations

The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia

M.M. Levi;T. van der Poll;H. ten Cate;S.J.H. van Deventer.
European Journal of Clinical Investigation (2003)

408 Citations

The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice

David J. van Westerloo;Ilona A. Giebelen;Sandrine Florquin;Marco J. Bruno.
Gastroenterology (2006)

405 Citations

Disseminated intravascular coagulation.

M. Levi;E. de Jonge;T. van der Poll;H. ten Cate.
Thrombosis and Haemostasis (1999)

391 Citations

Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.

T. Van Der Poll;J. Jansen;E. Endert;H. P. Sauerwein.
Infection and Immunity (1994)

370 Citations

Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans

T. Van Der Poll;J. A. Romijn;E. Endert;J. J. J. Borm.
American Journal of Physiology-endocrinology and Metabolism (1991)

347 Citations

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Best Scientists Citing T. van der Poll

Tom van der Poll

Tom van der Poll

University of Amsterdam

Publications: 270

Marcel Levi

Marcel Levi

University College London Hospitals NHS Foundation Trust

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Sandrine Florquin

Sandrine Florquin

University of Amsterdam

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Cornelis van 't Veer

Cornelis van 't Veer

University of Amsterdam

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Marcus J. Schultz

Marcus J. Schultz

University of Amsterdam

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Alex F. de Vos

Alex F. de Vos

University of Amsterdam

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Nicholas P. J. Day

Nicholas P. J. Day

University of Oxford

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Stephen F. Lowry

Stephen F. Lowry

Rutgers, The State University of New Jersey

Publications: 38

Steven M. Opal

Steven M. Opal

Brown University

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Nigel Mackman

Nigel Mackman

University of North Carolina at Chapel Hill

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Bente Klarlund Pedersen

Bente Klarlund Pedersen

University of Copenhagen

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Johannes A. Romijn

Johannes A. Romijn

University of Amsterdam

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Bernd Jilma

Bernd Jilma

Medical University of Vienna

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Sharon J. Peacock

Sharon J. Peacock

University of Cambridge

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Jean Louis Vincent

Jean Louis Vincent

Université Libre de Bruxelles

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Kevin J. Tracey

Kevin J. Tracey

Feinstein Institute for Medical Research

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