University of Amsterdam
T. van der Poll focuses on Internal medicine, Endocrinology, Tumor necrosis factor alpha, Cytokine and Immunology. In general Endocrinology study, his work on Inflammatory reflex, Acetylcholine and Vagus nerve often relates to the realm of GTS-21, thereby connecting several areas of interest. His Tumor necrosis factor alpha study integrates concerns from other disciplines, such as Pentoxifylline, Fibrinolysis, Coagulation and Bolus.
T. van der Poll interconnects Hormone and Stimulation in the investigation of issues within Cytokine. His studies in Immunology integrate themes in fields like Disseminated intravascular coagulation and Tuberculosis. His research integrates issues of Innate immune system, Pathogenesis and Endothelial dysfunction in his study of Sepsis.
The scientist’s investigation covers issues in Immunology, Internal medicine, Sepsis, Cytokine and Tumor necrosis factor alpha. T. van der Poll combines subjects such as Fibrinolysis, Coagulation and Pharmacology with his study of Immunology. The study incorporates disciplines such as Gastroenterology, Endocrinology and Surgery in addition to Internal medicine.
His Sepsis research is multidisciplinary, incorporating elements of Streptococcus pneumoniae, Pathogenesis, Pneumonia, Burkholderia pseudomallei and Intensive care medicine. The concepts of his Cytokine study are interwoven with issues in Stimulation, Pathophysiology and Tuberculosis. His Tumor necrosis factor alpha research incorporates elements of Neutrophil degranulation, Neutrophilia, Antibody, Monoclonal antibody and Receptor antagonist.
His primary areas of investigation include Immunology, Sepsis, Internal medicine, Intensive care medicine and In patient. His work investigates the relationship between Immunology and topics such as Coagulation that intersect with problems in Hemostasis. His Sepsis research is multidisciplinary, incorporating perspectives in Platelet activation, Endothelium and Intensive care unit.
With his scientific publications, his incorporates both Internal medicine and Canakinumab. He works mostly in the field of Intensive care medicine, limiting it down to topics relating to Antibiotic resistance and, in certain cases, Organ dysfunction, Sequential organ failure assessment and Etiology, as a part of the same area of interest. He studied Fibrinolysis and Meningitis that intersect with Inflammation.
T. van der Poll mostly deals with Immunology, Sepsis, Platelet, Internal medicine and Thrombin. His work in Immunology tackles topics such as Coagulation which are related to areas like Hemostasis. While the research belongs to areas of Sepsis, he spends his time largely on the problem of Endothelium, intersecting his research to questions surrounding Endothelial stem cell, Cytokine, P-selectin and Bone marrow.
His biological study spans a wide range of topics, including Fibrinogen, Pharmacology, Neutrophil extracellular traps and Fibrin. The Internal medicine study combines topics in areas such as Pediatrics and Pathology. His Thrombin study deals with Fibrinolysis intersecting with Placebo, Venous blood, Prednisolone and Gastroenterology.
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Activation of coagulation after administration of tumor necrosis factor to normal subjects.
T van der Poll;H R Büller;H ten Cate;C H Wortel.
The New England Journal of Medicine (1990)
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees
M Levi;H ten Cate;K A Bauer;T van der Poll.
Journal of Clinical Investigation (1994)
Pathogenesis of disseminated intravascular coagulation in sepsis
M. Levi;H. Ten Cate;T. Van Der Poll;S. J. H. Van Deventer.
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.
T van der Poll;M Levi;C E Hack;H ten Cate.
Journal of Experimental Medicine (1994)
Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.
D. Pajkrt;J. E. Doran;F. Koster;P. G. Lerch.
Journal of Experimental Medicine (1996)
The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice
David J. van Westerloo;Ilona A. Giebelen;Sandrine Florquin;Marco J. Bruno.
The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia
M.M. Levi;T. van der Poll;H. ten Cate;S.J.H. van Deventer.
European Journal of Clinical Investigation (2003)
Disseminated intravascular coagulation.
M. Levi;E. de Jonge;T. van der Poll;H. ten Cate.
Thrombosis and Haemostasis (1999)
Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.
T. Van Der Poll;J. Jansen;E. Endert;H. P. Sauerwein.
Infection and Immunity (1994)
Interleukin-6 stimulates coagulation, not fibrinolysis, in humans.
J. M. L. Stouthard;M. Levi;C. E. Hack;C. H. N. Veenhof.
Thrombosis and Haemostasis (1996)
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