D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 81 Citations 21,749 157 World Ranking 8997 National Ranking 4884

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Steven M. Paul mainly focuses on Internal medicine, Endocrinology, Genetically modified mouse, Alzheimer's disease and Apolipoprotein E. His Endocrinology research integrates issues from Ion channel complex, Receptor, Muscarinic acetylcholine receptor, GABAA receptor and Pharmacology. His research integrates issues of Biochemistry and Central nervous system in his study of Pharmacology.

His study in Genetically modified mouse is interdisciplinary in nature, drawing from both Amyloid precursor protein, Degenerative disease, Neuroscience, In vivo and Effector. His Alzheimer's disease research incorporates elements of Psychiatry, Neurite, Immunology and Amyloid. His study focuses on the intersection of Apolipoprotein E and fields such as Transgene with connections in the field of Pathogenesis and Apolipoproteins E.

His most cited work include:

  • How to improve R&D productivity: the pharmaceutical industry's grand challenge (2065 citations)
  • Steroid Hormone Metabolites are Barbiturate-Like Modulators of the GABA Receptor (1987 citations)
  • Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease (1248 citations)

What are the main themes of his work throughout his whole career to date?

Steven M. Paul mostly deals with Internal medicine, Endocrinology, Pharmacology, Apolipoprotein E and Cell biology. Alzheimer's disease and Agonist are the subjects of his Internal medicine studies. His Endocrinology study combines topics in areas such as Extracellular, In vivo and Binding site.

As part of the same scientific family, Steven M. Paul usually focuses on Pharmacology, concentrating on Benzodiazepine and intersecting with Diazepam. His Apolipoprotein E study combines topics from a wide range of disciplines, such as Molecular biology, LDL receptor and Genetically modified mouse, Transgene. Steven M. Paul combines subjects such as Apoptosis, Biochemistry and Neurotoxicity with his study of Cell biology.

He most often published in these fields:

  • Internal medicine (32.80%)
  • Endocrinology (31.19%)
  • Pharmacology (24.44%)

What were the highlights of his more recent work (between 2003-2021)?

  • Apolipoprotein E (20.26%)
  • Internal medicine (32.80%)
  • Endocrinology (31.19%)

In recent papers he was focusing on the following fields of study:

Steven M. Paul spends much of his time researching Apolipoprotein E, Internal medicine, Endocrinology, Genetically modified mouse and Alzheimer's disease. His work in Apolipoprotein E addresses subjects such as Apolipoprotein B, which are connected to disciplines such as Serum amyloid A. His studies deal with areas such as Schizophrenia and Antipsychotic as well as Internal medicine.

His Endocrinology study integrates concerns from other disciplines, such as Receptor and ABCA1. His biological study spans a wide range of topics, including Neurodegeneration, Immunology, Amyloid precursor protein and Hippocampal formation, Neuroscience. Steven M. Paul has researched Alzheimer's disease in several fields, including Hippocampus, Cerebrospinal fluid, Transgene and Amyloid.

Between 2003 and 2021, his most popular works were:

  • How to improve R&D productivity: the pharmaceutical industry's grand challenge (2065 citations)
  • Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo (887 citations)
  • P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model (494 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

The scientist’s investigation covers issues in Apolipoprotein E, Amyloid precursor protein, Genetically modified mouse, Alzheimer's disease and Endocrinology. His work deals with themes such as Cerebral amyloid angiopathy and Amyloid, which intersect with Amyloid precursor protein. His Genetically modified mouse study incorporates themes from Senile plaques, Extracellular, Hippocampal formation, Neuroscience and Neuroinflammation.

His Alzheimer's disease research includes elements of Immunology, Transgene and Tauopathy. His work carried out in the field of Endocrinology brings together such families of science as Internal medicine, Glycogen synthase and ABCA1. Steven M. Paul is interested in Neuroprotection, which is a field of Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

How to improve R&D productivity: the pharmaceutical industry's grand challenge

Steven M. Paul;Daniel S. Mytelka;Christopher T. Dunwiddie;Charles C. Persinger.
Nature Reviews Drug Discovery (2010)

3259 Citations

Steroid Hormone Metabolites are Barbiturate-Like Modulators of the GABA Receptor

Majewska;NL Harrison;RD Schwartz;JL Barker.
Science (1986)

2487 Citations

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

Ronald B. DeMattos;Kelly R. Bales;David J. Cummins;Jean-Cosme Dodart.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1608 Citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

PB Clarke;RD Schwartz;SM Paul;CB Pert.
The Journal of Neuroscience (1985)

1239 Citations

Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

Jean Cosme Dodart;Kelly R. Bales;Kimberley S. Gannon;Stephen J. Greene.
Nature Neuroscience (2002)

1159 Citations

Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo

John R. Cirrito;Kelvin A. Yamada;Mary Beth Finn;Robert S. Sloviter.
Neuron (2005)

1115 Citations

Receptors for the age of anxiety: pharmacology of the benzodiazepines

John F. Tallman;Steven M. Paul;Phil Skolnick;Dorothy W. Gallager.
Science (1980)

1050 Citations

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

David M. Holtzman;Kelly R. Bales;Tanya Tenkova;Anne M. Fagan.
Proceedings of the National Academy of Sciences of the United States of America (2000)

1018 Citations

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

Yansheng Du;Zhizhong Ma;Suizhen Lin;Richard C. Dodel.
Proceedings of the National Academy of Sciences of the United States of America (2001)

861 Citations

Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.

Peter D. Suzdak;Rochelle D. Schwartz;Phil Skolnick;Steven M. Paul.
Proceedings of the National Academy of Sciences of the United States of America (1986)

692 Citations

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