Nigel J. Cairns focuses on Alzheimer's disease, Pathology, Dementia, Disease and Frontotemporal lobar degeneration. The concepts of his Alzheimer's disease study are interwoven with issues in Central nervous system disease and Degenerative disease. His Pathology study frequently draws parallels with other fields, such as Gene mutation.
The study incorporates disciplines such as Cerebral cortex, Cancer research and Pathological in addition to Dementia. His work deals with themes such as Biomarker, Genetics, Neuroscience and Gerontology, which intersect with Disease. His Frontotemporal lobar degeneration research includes elements of Neuropathology, Amyotrophic lateral sclerosis and Ubiquitin.
Nigel J. Cairns spends much of his time researching Pathology, Alzheimer's disease, Disease, Dementia and Neuroscience. Cerebral cortex is closely connected to Hippocampus in his research, which is encompassed under the umbrella topic of Pathology. The Alzheimer's disease study combines topics in areas such as Central nervous system disease and Degenerative disease.
His Disease study integrates concerns from other disciplines, such as Biomarker and Neuroimaging. In his study, Cognitive decline is strongly linked to Cognition, which falls under the umbrella field of Dementia. The various areas that Nigel J. Cairns examines in his Frontotemporal lobar degeneration study include Mutation, Amyotrophic lateral sclerosis and Cytoplasmic inclusion.
Pathology, Alzheimer's disease, Disease, Dementia and Internal medicine are his primary areas of study. His research in the fields of Tauopathy, Senile plaques and Cerebrospinal fluid overlaps with other disciplines such as Chronic traumatic encephalopathy. His Alzheimer's disease research incorporates elements of Neuropathology, Magnetic resonance imaging, Neuroimaging and Cognitive decline.
His research in Disease focuses on subjects like Neuroscience, which are connected to Hyperintensity, Neuroinflammation and Atrophy. His work on Lewy body as part of general Dementia research is frequently linked to Hippocampal sclerosis, thereby connecting diverse disciplines of science. His study in Internal medicine is interdisciplinary in nature, drawing from both Endocrinology, Allele and Oncology.
His primary areas of investigation include Alzheimer's disease, Pathology, Dementia, Disease and Tauopathy. His research in Alzheimer's disease intersects with topics in Pathological, Brain mapping, Cognitive decline, Biomarker and Atrophy. His Clinical Dementia Rating study in the realm of Pathology interacts with subjects such as Chronic traumatic encephalopathy.
Dementia is a primary field of his research addressed under Internal medicine. His Disease study combines topics in areas such as Neuroimaging and Neuroscience. His studies deal with areas such as Positron emission tomography, Tau protein and Cerebrospinal fluid as well as Tauopathy.
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Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease
Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan.
The New England Journal of Medicine (2012)
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Bradley T. Hyman;Creighton H. Phelps;Thomas G. Beach;Eileen H. Bigio.
Alzheimers & Dementia (2012)
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang.
Nature Genetics (2011)
National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
Thomas J. Montine;Creighton H. Phelps;Thomas G. Beach;Eileen H. Bigio.
Acta Neuropathologica (2012)
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T Nelson;Irina Alafuzoff;Eileen H Bigio;Constantin Bouras.
Journal of Neuropathology and Experimental Neurology (2012)
Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms
M. Goedert;M.G. Spillantini;N.J. Cairns;R.A. Crowther.
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
Nigel J. Cairns;Eileen H. Bigio;Ian R A Mackenzie;Manuela Neumann.
Acta Neuropathologica (2007)
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.
Michael W. Weiner;Michael W. Weiner;Dallas P. Veitch;Paul S. Aisen;Laurel A Beckett.
Alzheimers & Dementia (2012)
Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
M G Spillantini;R A Crowther;R Jakes;N J Cairns.
Neuroscience Letters (1998)
Primary age-related tauopathy (PART): a common pathology associated with human aging
John F. Crary;John Q. Trojanowski;Julie A. Schneider;Jose F. Abisambra.
Acta Neuropathologica (2014)
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