D-Index & Metrics Best Publications
Masahiro Fujita

Masahiro Fujita

Houston Methodist
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Cancer
  • Surgery

His scientific interests lie mostly in Radioligand, Pathology, Internal medicine, Endocrinology and Positron emission tomography. His Radioligand research incorporates themes from Peripheral, Microglia and GABAA receptor. Masahiro Fujita interconnects Biomarker and Receptor, PK-11195, Ligand in the investigation of issues within Pathology.

His Endocrinology research integrates issues from Medial frontal gyrus, Iomazenil, Benzodiazepine and Inferior frontal gyrus. His work carried out in the field of Neuroimaging brings together such families of science as Nuclear medicine, Human brain and Electroencephalography. His Radioligand Assay study integrates concerns from other disciplines, such as Preclinical imaging, DASB, Molecular imaging, Constant infusion and Computational biology.

His most cited work include:

  • Consensus nomenclature for in vivo imaging of reversibly binding radioligands (1571 citations)
  • Molecular imaging of the dopaminergic system and its association with human cognitive function. (259 citations)
  • Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands (245 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Radioligand, Internal medicine, Endocrinology, Nuclear medicine and Positron emission tomography. His Radioligand research is multidisciplinary, relying on both Dosimetry, Pharmacology, Human brain and Pathology. In his research on the topic of Pathology, Microglia is strongly related with Peripheral.

His Internal medicine study combines topics from a wide range of disciplines, such as Major depressive disorder, Psychiatry and Oncology. The Endocrinology study combines topics in areas such as Rolipram, Benzodiazepine and Ligand. His Nuclear medicine research includes themes of Putamen, Distribution Volume, Reproducibility, Tomography and Voxel.

He most often published in these fields:

  • Radioligand (30.00%)
  • Internal medicine (29.50%)
  • Endocrinology (25.50%)

What were the highlights of his more recent work (between 2015-2021)?

  • Radioligand (30.00%)
  • Translocator protein (14.00%)
  • Pathology (15.50%)

In recent papers he was focusing on the following fields of study:

Masahiro Fujita mainly investigates Radioligand, Translocator protein, Pathology, Positron emission tomography and Neuroinflammation. His research in Radioligand intersects with topics in Nuclear medicine, Model selection, Radiochemistry, Cyclooxygenase and Neuroscience. Translocator protein is a subfield of Internal medicine that Masahiro Fujita investigates.

His studies in Pathology integrate themes in fields like Preclinical imaging and Carotid endarterectomy. His Positron emission tomography study incorporates themes from Rolipram, Receptor, Pharmacology and Human brain. His Receptor research incorporates elements of Cerebellum and Effective dose.

Between 2015 and 2021, his most popular works were:

  • 11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain. (94 citations)
  • PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects (74 citations)
  • Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios. (43 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Cancer
  • Surgery

Masahiro Fujita focuses on Human brain, Positron emission tomography, Translocator protein, Pathology and Radioligand. His research integrates issues of Cerebellum and Receptor, Biochemistry in his study of Human brain. His Positron emission tomography study frequently links to related topics such as Pharmacology.

As part of one scientific family, Masahiro Fujita deals mainly with the area of Translocator protein, narrowing it down to issues related to the Biomarker, and often Endocrinology. The various areas that he examines in his Radioligand study include Nuclear medicine, Model selection, Biological system, Arterial plasma and Reference values. His studies deal with areas such as Anterior cingulate cortex and Prefrontal cortex as well as Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Consensus nomenclature for in vivo imaging of reversibly binding radioligands

Robert B. Innis;Vincent Joseph Cunningham;Jacques Delforge;Masahiro Fujita.
Journal of Cerebral Blood Flow and Metabolism (2007)

1977 Citations

Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

David R.J. Owen;Roger N. Gunn;Eugenii A. Rabiner;Idriss Bennacef.
The Journal of Nuclear Medicine (2011)

369 Citations

Molecular imaging of the dopaminergic system and its association with human cognitive function.

Vanessa L Cropley;Vanessa L Cropley;Masahiro Fujita;Robert B Innis;Pradeep Jonathan Nathan.
Biological Psychiatry (2006)

332 Citations

Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.

William C. Kreisl;Masahiro Fujita;Yota Fujimura;Yota Fujimura;Nobuyo Kimura.
NeuroImage (2010)

324 Citations

Increase in Prefrontal Cortex Serotonin2A Receptors Following Estrogen Treatment in Postmenopausal Women

Akira Kugaya;C. Neill Epperson;Sami Zoghbi;Christopher H. van Dyck.
American Journal of Psychiatry (2003)

283 Citations

Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers

Julie K. Staley;Suchitra Krishnan-Sarin;Sami Zoghbi;Gilles Tamagnan.
Synapse (2001)

281 Citations

SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder.

J.Douglas Bremner;Robert B Innis;Thomas White;Masahiro Fujita.
Biological Psychiatry (2000)

274 Citations

Image-derived input function for brain PET studies: many challenges and few opportunities.

Paolo Zanotti-Fregonara;Kewei Chen;Jeih San Liow;Masahiro Fujita.
Journal of Cerebral Blood Flow and Metabolism (2011)

210 Citations

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.

Masahiro Fujita;Masao Imaizumi;Sami S. Zoghbi;Yota Fujimura.
NeuroImage (2008)

204 Citations

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.

Emmanuelle Briard;Sami S. Zoghbi;Masao Imaizumi;Jonathan P. Gourley.
Journal of Medicinal Chemistry (2008)

197 Citations

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