What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Catalysis
- Enzyme
His main research concerns Organic chemistry, Catalysis, Click chemistry, Combinatorial chemistry and Cycloaddition.
His Organic chemistry study frequently involves adjacent topics like Medicinal chemistry.
The Dihydroxylation, Enantioselective synthesis and Osmium Compounds research he does as part of his general Catalysis study is frequently linked to other disciplines of science, such as Terminal, therefore creating a link between diverse domains of science.
His Click chemistry study combines topics in areas such as In situ, Acetylcholinesterase, Reactivity and Copper.
His Combinatorial chemistry research is multidisciplinary, relying on both Photochemistry, Molecule and Coumarin.
His Cycloaddition study also includes
- Azide and related Alkyne, Triazole, Stereochemistry, Substituent and Conformational isomerism,
- Nitrile together with 1,3-Dipolar cycloaddition.
His most cited work include:
- A Stepwise Huisgen Cycloaddition Process: Copper(I)‐Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes (8497 citations)
- Click Chemistry: Diverse Chemical Function from a Few Good Reactions. (8427 citations)
- Catalytic Asymmetric Dihydroxylation (2654 citations)
What are the main themes of his work throughout his whole career to date?
K. Barry Sharpless mainly investigates Organic chemistry, Catalysis, Stereochemistry, Dihydroxylation and Combinatorial chemistry.
His studies deal with areas such as Vicinal, Nitrogen source, Ligand and Medicinal chemistry as well as Catalysis.
His research investigates the link between Stereochemistry and topics such as Acetylcholinesterase that cross with problems in Oxime.
His Dihydroxylation research includes themes of Chiral ligand, Enantiomeric excess and Hydroxylation.
K. Barry Sharpless does research in Combinatorial chemistry, focusing on Click chemistry specifically.
His Click chemistry course of study focuses on Cycloaddition and Azide, Copper and Triazole derivatives.
He most often published in these fields:
- Organic chemistry (49.06%)
- Catalysis (34.67%)
- Stereochemistry (21.70%)
What were the highlights of his more recent work (between 2009-2021)?
- Click chemistry (16.75%)
- Combinatorial chemistry (17.92%)
- Stereochemistry (21.70%)
In recent papers he was focusing on the following fields of study:
K. Barry Sharpless mainly focuses on Click chemistry, Combinatorial chemistry, Stereochemistry, Organic chemistry and Polymer chemistry.
K. Barry Sharpless has researched Click chemistry in several fields, including Reactivity, Thionyl tetrafluoride, Sulfur and Sulfonyl.
His work carried out in the field of Combinatorial chemistry brings together such families of science as In situ, Nucleophile and Drug discovery.
The various areas that K. Barry Sharpless examines in his Stereochemistry study include Oxime, Acetylcholine binding, Cyclosarin, Ion channel and Triazole.
His Organic chemistry study focuses mostly on Catalysis, Cycloaddition and Azide.
His Catalysis research includes elements of Moiety, Ligand and Copper.
Between 2009 and 2021, his most popular works were:
- Copper catalyzed cycloaddition of organic azides and 1-haloalkynes (336 citations)
- Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry (319 citations)
- SuFEx‐Based Synthesis of Polysulfates (103 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Catalysis
- Enzyme
K. Barry Sharpless spends much of his time researching Organic chemistry, Catalysis, Click chemistry, Polymer chemistry and Combinatorial chemistry.
In most of his Organic chemistry studies, his work intersects topics such as Metabolite.
The study of Catalysis is intertwined with the study of Tertiary amine in a number of ways.
In his research, Difluoride is intimately related to Sulfur, which falls under the overarching field of Click chemistry.
His Polymer chemistry research also works with subjects such as
- Michael reaction that intertwine with fields like Bisphenol, Monomer, Condensation polymer, Side chain and Amine gas treating,
- Alkyl, Bifluoride, Polycarbonate, Dimethyl formamide and Polymer most often made with reference to Silylation.
His Combinatorial chemistry study combines topics from a wide range of disciplines, such as In situ, Acetylcholinesterase, Small molecule and Drug discovery.
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