D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 42 Citations 19,789 60 World Ranking 15584 National Ranking 6450

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Phosphorylation
  • Signal transduction

J T Parsons focuses on Tyrosine phosphorylation, Molecular biology, Proto-oncogene tyrosine-protein kinase Src, PTK2 and SH3 domain. His study with Tyrosine phosphorylation involves better knowledge in Phosphorylation. His study looks at the relationship between Molecular biology and fields such as Receptor tyrosine kinase, as well as how they intersect with chemical problems.

Proto-oncogene tyrosine-protein kinase Src is closely attributed to Protein tyrosine phosphatase in his work. His PTK2 research is multidisciplinary, incorporating elements of Cyclin-dependent kinase 9, Integrin, Paxillin, Focal adhesion and Focal Adhesion Kinase 2. His SH3 domain research integrates issues from Podosome, Peptide sequence, SH2 domain, Actin and Subcellular localization.

His most cited work include:

  • pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. (1268 citations)
  • Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. (1125 citations)
  • Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. (646 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Proto-oncogene tyrosine-protein kinase Src, Cell biology, Molecular biology, Tyrosine phosphorylation and Phosphorylation. His studies deal with areas such as Avian sarcoma virus, Tyrosine kinase and Receptor tyrosine kinase as well as Proto-oncogene tyrosine-protein kinase Src. In Cell biology, J T Parsons works on issues like Cytoskeleton, which are connected to Actin.

His Molecular biology research is multidisciplinary, incorporating perspectives in Phenotype, Transfection and Protein kinase A. His Tyrosine phosphorylation research focuses on Protein phosphorylation and how it connects with LYN. In his research on the topic of Phosphorylation, Epidermal growth factor, Kinase and Cellular proteins is strongly related with Tyrosine.

He most often published in these fields:

  • Proto-oncogene tyrosine-protein kinase Src (53.70%)
  • Cell biology (51.85%)
  • Molecular biology (44.44%)

What were the highlights of his more recent work (between 1998-2014)?

  • Cell biology (51.85%)
  • Focal adhesion (29.63%)
  • Cell adhesion (11.11%)

In recent papers he was focusing on the following fields of study:

J T Parsons spends much of his time researching Cell biology, Focal adhesion, Cell adhesion, Molecular biology and Computational biology. The study incorporates disciplines such as Cell cycle and Cytoskeleton in addition to Cell biology. His work deals with themes such as Neurite, Cell morphology and CDC42, GTPase, which intersect with Focal adhesion.

J T Parsons has included themes like Cell migration, Cell movement and Myosin in his Cell adhesion study. J T Parsons performs multidisciplinary study in Molecular biology and Vascular smooth muscle in his work. J T Parsons has researched Computational biology in several fields, including Tyrosine kinase, Genetics, Proto-oncogene tyrosine-protein kinase Src and Cdna cloning.

Between 1998 and 2014, his most popular works were:

  • Cell migration--movin' on. (353 citations)
  • Selective Expression of an Endogenous Inhibitor of FAK Regulates Proliferation and Migration of Vascular Smooth Muscle Cells (143 citations)
  • Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho. (88 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Phosphorylation
  • Signal transduction

J T Parsons mainly investigates Cell biology, Cell adhesion, Focal adhesion, Cell migration and Microtubule dynamics. His work on Cytoskeleton expands to the thematically related Cell biology. His Cytoskeleton research incorporates elements of Cell morphology, CDC42, GTPase and Neurite.

His work carried out in the field of Cell migration brings together such families of science as Cell movement and Myosin. His Extracellular matrix research incorporates themes from Molecular biology, Platelet-derived growth factor, Platelet-derived growth factor receptor and Ectopic expression. His work on Stress fiber is being expanded to include thematically relevant topics such as Actin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

M D Schaller;C A Borgman;B S Cobb;R R Vines.
Proceedings of the National Academy of Sciences of the United States of America (1992)

2016 Citations

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

M D Schaller;J D Hildebrand;J D Shannon;J W Fox.
Molecular and Cellular Biology (1994)

1510 Citations

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

L Kornberg;H S Earp;J T Parsons;M Schaller.
Journal of Biological Chemistry (1992)

1005 Citations

Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement

J T Parsons;K H Martin;J K Slack;J M Taylor.
Oncogene (2000)

904 Citations

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.

M D Schaller;C A Otey;J D Hildebrand;J T Parsons.
Journal of Cell Biology (1995)

823 Citations

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.

L Lipfert;B Haimovich;M D Schaller;B S Cobb.
Journal of Cell Biology (1992)

821 Citations

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk.

M D Schaller;J T Parsons.
Molecular and Cellular Biology (1995)

757 Citations

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

B. S. Cobb;M. D. Schaller;Tzeng-Horng Leu;J. T. Parsons.
Molecular and Cellular Biology (1994)

728 Citations

Focal adhesion kinase and associated proteins

M D Schaller;J T Parsons.
Current Opinion in Cell Biology (1994)

728 Citations

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.

Hong Wu;J. T. Parsons.
Journal of Cell Biology (1993)

723 Citations

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