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Hilary Koprowski

Hilary Koprowski

The Wistar Institute
United States

Research.com Recognitions

Awards & Achievements

1992 - Fellow of the American Association for the Advancement of Science (AAAS)

1976 - Member of the National Academy of Sciences

Overview

What is she best known for?

The fields of study she is best known for:

Gene
Virus
Antibody

Hilary Koprowski mainly focuses on Molecular biology, Antibody, Virology, Monoclonal antibody and Virus. Her work carried out in the field of Molecular biology brings together such families of science as Complementary DNA, Molecular cloning, Gene, Receptor and Spleen. Her studies in Antibody integrate themes in fields like Cell culture, Interferon and Cytotoxicity.

Her Virology study integrates concerns from other disciplines, such as Epitope, Virus Cultivation and DNA. Her studies deal with areas such as Adenocarcinoma, Cancer research, Antigen and Pathology as well as Monoclonal antibody. Her Virus research is multidisciplinary, relying on both Tumor Virus, Cell nucleus and In vitro, Tissue culture.

Her most cited work include:

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin (562 citations)
Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies (541 citations)
Specific antigen in serum of patients with colon carcinoma (494 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Virology, Molecular biology, Monoclonal antibody, Antigen and Antibody. Her Virology study frequently draws parallels with other fields, such as Epitope. Within one scientific family, Hilary Koprowski focuses on topics pertaining to Cell culture under Molecular biology, and may sometimes address concerns connected to Tissue culture.

In her study, Ganglioside is inextricably linked to Melanoma, which falls within the broad field of Monoclonal antibody. The various areas that Hilary Koprowski examines in her Antigen study include Carcinoembryonic antigen, Pan-T antigens and Glycoprotein. Her work carried out in the field of Antibody brings together such families of science as In vitro, Cytotoxicity and In vivo.

She most often published in these fields:

Virology (41.87%)
Molecular biology (35.20%)
Monoclonal antibody (31.20%)

What were the highlights of her more recent work (between 1993-2017)?

Virology (41.87%)
Molecular biology (35.20%)
Rabies virus (16.27%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Virology, Molecular biology, Rabies virus, Antigen and Virus. The Virology study combines topics in areas such as Alfalfa mosaic virus, Gene, Recombinant DNA and Immune system. She combines subjects such as Transgene, Biochemistry, Northern blot, Cytotoxicity and CD3 with her study of Molecular biology.

Her work deals with themes such as In vitro, Monoclonal antibody, Polymerase chain reaction and Protein biosynthesis, which intersect with Antigen. Her study on Monoclonal antibody is covered under Antibody. Her study in Virus is interdisciplinary in nature, drawing from both Molecular genetics and Cancer research.

Between 1993 and 2017, her most popular works were:

Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis (452 citations)
Function and glycosylation of plant-derived antiviral monoclonal antibody (221 citations)
Identification of viral genomic elements responsible for rabies virus neuroinvasiveness (115 citations)

In her most recent research, the most cited papers focused on:

Gene
Virus
Enzyme

Her primary areas of study are Virology, Molecular biology, Antigen, Rabies virus and Recombinant DNA. Her study in Virology focuses on Virus in particular. Her Virus research is multidisciplinary, incorporating elements of Complementary DNA and Virulence.

She has included themes like Biochemistry, Northern blot, Nucleoprotein, Multiple sclerosis and Phosphoprotein in her Molecular biology study. Her biological study spans a wide range of topics, including Monoclonal antibody and Protein biosynthesis. Her Monoclonal antibody research also works with subjects such as

Transgene and related In vitro, Cytotoxicity and Cancer immunotherapy,
KDEL and Antibody most often made with reference to Glycosylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin

John L. Magnani;Zenon Steplewski;Hilary Koprowski;Victor Ginsburg.
Cancer Research (1983)

878 Citations

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies

Meenhard Herlyn;Zenon Steplewski;Dorothee Herlyn;Hilary Koprowski.
Proceedings of the National Academy of Sciences of the United States of America (1979)

868 Citations

Specific antigen in serum of patients with colon carcinoma

Hilary Koprowski;Meenhard Herlyn;Zenon Steplewski;Henry F. Sears.
Science (1981)

786 Citations

Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis.

Omar Bagasra;Frank H. Michaels;Yong Mu Zheng;Lisa E. Bobroski.
Proceedings of the National Academy of Sciences of the United States of America (1995)

629 Citations

Gene transfer and molecular cloning of the human NGF receptor

MV Chao;MA Bothwell;AH Ross;H Koprowski.
Science (1986)

605 Citations

Gastrointestinal cancer-associated antigen in immunoperoxidase assay.

Barbara F. Atkinson;Carolyn S. Ernst;Meenhard Herlyn;Zenon Steplewski.
Cancer Research (1982)

587 Citations

A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma.

John L. Magnani;Manfred Brockhaus;David F. Smith;Victor Ginsburg.
Science (1981)

531 Citations

INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUS

Fred C. Jensen;Anthony J. Girardi;Raymond V. Gilden;Hilary Koprowski.
Proceedings of the National Academy of Sciences of the United States of America (1964)

486 Citations

Study of antibodies against human melanoma produced by somatic cell hybrids.

Hilary Koprowski;Zenon Steplewski;Dorothee Herlyn;Meenhard Herlyn.
Proceedings of the National Academy of Sciences of the United States of America (1978)

464 Citations

Method of producing antibodies

Hilary Koprowski;Walter U. Gerhard;Carlo M. Croce.
(1978)

458 Citations

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