D-Index & Metrics Best Publications
henry a erlich

henry a erlich

Children's Hospital Oakland Research Institute
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His primary areas of study are Genetics, Polymerase chain reaction, Molecular biology, Nucleic acid thermodynamics and Biochemistry. His biological study spans a wide range of topics, including Gene duplication, Oligonucleotide, STR analysis and genomic DNA. Henry A. Erlich combines subjects such as Hybridization probe, Multiple displacement amplification, Mitochondrial DNA, DNA polymerase and Sanger sequencing with his study of Molecular biology.

His work is dedicated to discovering how Multiple displacement amplification, Inverse polymerase chain reaction are connected with Amplicon and Digital polymerase chain reaction and other disciplines. Henry A. Erlich studies Nucleic acid, a branch of Biochemistry. His Taq polymerase study integrates concerns from other disciplines, such as Hot start PCR, Pfu DNA polymerase and Polymerase.

His most cited work include:

  • Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase (14961 citations)
  • Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes (1866 citations)
  • Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme (1837 citations)

What are the main themes of his work throughout his whole career to date?

Henry A. Erlich spends much of his time researching Genetics, Molecular biology, Human leukocyte antigen, Polymerase chain reaction and Allele. The various areas that Henry A. Erlich examines in his Molecular biology study include Hybridization probe, Multiple displacement amplification, Nucleic acid, Oligonucleotide and DNA sequencing. Henry A. Erlich interconnects Multiplex polymerase chain reaction, Inverse polymerase chain reaction, Nested polymerase chain reaction and Real-time polymerase chain reaction in the investigation of issues within Multiple displacement amplification.

His work carried out in the field of Inverse polymerase chain reaction brings together such families of science as Hot start PCR and Applications of PCR. The Polymerase chain reaction study combines topics in areas such as genomic DNA, Gene duplication and Genotype. His research in Nucleic acid sequence intersects with topics in DNA polymerase and HLA-DR Antigen.

He most often published in these fields:

  • Genetics (48.39%)
  • Molecular biology (39.78%)
  • Human leukocyte antigen (27.96%)

What were the highlights of his more recent work (between 1991-2020)?

  • Genetics (48.39%)
  • Human leukocyte antigen (27.96%)
  • Gene (19.35%)

In recent papers he was focusing on the following fields of study:

Henry A. Erlich mostly deals with Genetics, Human leukocyte antigen, Gene, Allele and Polymerase chain reaction. Henry A. Erlich performs integrative Genetics and Peripheral blood mononuclear cell research in his work. His Human leukocyte antigen research is multidisciplinary, relying on both Multiple displacement amplification and MHC class I.

Locus, Genotype, Variable number tandem repeat, Taq polymerase and Genetic marker are subfields of Gene in which his conducts study. His work in the fields of HLA-DPB1 and Polymorphism overlaps with other areas such as West african and West africa. His study in Polymerase chain reaction is interdisciplinary in nature, drawing from both Reverse transcription polymerase chain reaction, Negroid, Typing and Molecular biology.

Between 1991 and 2020, his most popular works were:

  • Preferential PCR amplification of alleles: mechanisms and solutions. (334 citations)
  • Nomenclature for Factors of the HLA System, 1991 (285 citations)
  • Nomenclature for factors of the HLA system, 1998. (229 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

His scientific interests lie mostly in Genetics, Human leukocyte antigen, MHC class I, Allele and Gene. His work on Polymerase chain reaction, Nomenclature Committee, Taq polymerase and Multiple displacement amplification as part of general Genetics study is frequently linked to Human genome, bridging the gap between disciplines. Henry A. Erlich has included themes like HLA-DR locus, Histocompatibility and MHC class II in his Nomenclature Committee study.

His Taq polymerase research includes themes of Genetic marker, Locus and Variable number tandem repeat, Genotype. The study incorporates disciplines such as Reverse transcription polymerase chain reaction, Multiplex polymerase chain reaction, Real-time polymerase chain reaction, Molecular biology and Typing in addition to Multiple displacement amplification. His research on Multiplex polymerase chain reaction frequently links to adjacent areas such as Nested polymerase chain reaction.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

Randall K. Saiki;David H. Gelfand;Susanne Stoffel;Stephen J. Scharf.
Science (1988)

22875 Citations

Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes.

Randall K. Saiki;Teodorica L. Bugawan;Glenn T. Horn;Kary B. Mullis.
Nature (1986)

3237 Citations

Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme

Kary B. Mullis;Henry A. Erlich;David H. Gelfand;Glenn Horn.
(1987)

2969 Citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus

Ulf B. Gyllensten;Henry A. Erlich.
Proceedings of the National Academy of Sciences of the United States of America (1988)

2311 Citations

Recent advances in the polymerase chain reaction

Henry A. Erlich;David Gelfand;John J. Sninsky.
Science (1991)

1654 Citations

DNA typing from single hairs

Higuchi R;von Beroldingen Ch;Sensabaugh Gf;Erlich Ha.
Nature (1988)

1077 Citations

Amplification and analysis of DNA sequences in single human sperm and diploid cells

Honghua Li;Ulf B. Gyllensten;Xiangfeng Cui;Randall K. Saiki.
Nature (1988)

902 Citations

Characterization of β-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA

Corinne Wong;Carol E. Dowling;Randall K. Saiki;Russell G. Higuchi.
Nature (1987)

726 Citations

Preferential PCR amplification of alleles: mechanisms and solutions.

P S Walsh;H A Erlich;R Higuchi.
Genome Research (1992)

529 Citations

Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA

Lisa A. Wrischnik;Russell G. Higuchi;Mark Stoneking;Henry A. Erlich.
Nucleic Acids Research (1987)

514 Citations

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