D-Index & Metrics Best Publications
Gary A. Jarvis

Gary A. Jarvis

Veterans Health Administration
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Enzyme
  • Antibody

Gary A. Jarvis mainly investigates Microbiology, Biochemistry, Antibody, Bacterial outer membrane and Epitope. His study in Microbiology focuses on Neisseria gonorrhoeae in particular. His Neisseria gonorrhoeae study combines topics from a wide range of disciplines, such as Infectivity, Secretion, Innate immune system and Cathepsin B.

His work in the fields of Transmembrane domain, Streptococcaceae and Platelet membrane glycoprotein overlaps with other areas such as Periplasmic space. The study incorporates disciplines such as Neisseria meningitidis, Neisseriaceae and Antigen in addition to Antibody. His study looks at the intersection of Epitope and topics like Monoclonal antibody with Gel electrophoresis, Immunoelectron microscopy and Staining.

His most cited work include:

  • Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome (216 citations)
  • Sialic acid of group B Neisseria meningitidis regulates alternative complement pathway activation. (147 citations)
  • Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. (126 citations)

What are the main themes of his work throughout his whole career to date?

Gary A. Jarvis mainly investigates Microbiology, Neisseria gonorrhoeae, Neisseria meningitidis, Lipid A and Biochemistry. In his works, Gary A. Jarvis conducts interdisciplinary research on Microbiology and Bacterial outer membrane. His Neisseria gonorrhoeae research includes elements of In vitro, Cytotoxicity, Molecular biology, THP1 cell line and Peptide.

His studies deal with areas such as Lectin, Mannan-binding lectin and Complement system as well as Neisseria meningitidis. His Lipid A research incorporates elements of Drug design, Secretion, Signal transduction, Phosphorylation and Proinflammatory cytokine. His work investigates the relationship between Biochemistry and topics such as Neisseria that intersect with problems in TLR4.

He most often published in these fields:

  • Microbiology (96.23%)
  • Neisseria gonorrhoeae (40.57%)
  • Neisseria meningitidis (34.91%)

What were the highlights of his more recent work (between 2015-2020)?

  • Lipid A (34.91%)
  • Microbiology (96.23%)
  • Bacterial outer membrane (32.08%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Lipid A, Microbiology, Bacterial outer membrane, Biochemistry and Innate immune system. He works mostly in the field of Lipid A, limiting it down to topics relating to Oligosaccharide and, in certain cases, Chromatography and Glycolipid. Particularly relevant to Neisseria gonorrhoeae is his body of work in Microbiology.

The Transmembrane domain, Drug design and Transferase research he does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as Phospholipid and Alpha helix, therefore creating a link between diverse domains of science. He has included themes like Proinflammatory cytokine, Neisseria meningitidis and Meningitis in his Innate immune system study. His Neisseria meningitidis research is multidisciplinary, incorporating perspectives in Acquired immune system, Immune tolerance, Immunology, Immune system and Signal transduction.

Between 2015 and 2020, his most popular works were:

  • Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding (77 citations)
  • Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding (77 citations)
  • Lipooligosaccharide Structures of Invasive and Carrier Isolates of Neisseria meningitidis Are Correlated with Pathogenicity and Carriage (13 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome

Joseph A. Duncan;Xi Gao;Max Tze Han Huang;Brian P. O'Connor.
Journal of Immunology (2009)

297 Citations

Sialic acid of group B Neisseria meningitidis regulates alternative complement pathway activation.

Gary A. Jarvis;Neylan A. Vedros.
Infection and Immunity (1987)

237 Citations

Human natural anti-Gal IgG regulates alternative complement pathway activation on bacterial surfaces.

R M Hamadeh;G A Jarvis;U Galili;R E Mandrell.
Journal of Clinical Investigation (1992)

185 Citations

Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer.

Constance M. John;Hakon Leffler;Barbro Kahl-Knutsson;Inga Svensson.
Clinical Cancer Research (2003)

177 Citations

Lipooligosaccharides: the principal glycolipids of the neisserial outer membrane.

J M Griffiss;H Schneider;R E Mandrell;R Yamasaki.
Clinical Infectious Diseases (1988)

164 Citations

Candidate Sulfonated and Sulfated Topical Microbicides: Comparison of Anti-Human Immunodeficiency Virus Activities and Mechanisms of Action

Irini A. Scordi-Bello;Arevik Mosoian;Cejiang He;Yiban Chen.
Antimicrobial Agents and Chemotherapy (2005)

158 Citations

Phenotypic variation in epitope expression of the Neisseria gonorrhoeae lipooligosaccharide.

M A Apicella;M Shero;G A Jarvis;J M Griffiss.
Infection and Immunity (1987)

157 Citations

Binding of the Streptococcus gordonii surface glycoproteins GspB and Hsa to specific carbohydrate structures on platelet membrane glycoprotein ibα

Daisuke Takamatsu;Barbara A. Bensing;Hui Cheng;Gary A. Jarvis.
Molecular Microbiology (2005)

150 Citations

Sialylation of Neisseria meningitidis lipooligosaccharide inhibits serum bactericidal activity by masking lacto-N-neotetraose.

M M Estabrook;J M Griffiss;G A Jarvis.
Infection and Immunity (1997)

135 Citations

Human IgA1 blockade of IgG-initiated lysis of Neisseria meningitidis is a function of antigen-binding fragment binding to the polysaccharide capsule.

G A Jarvis;J M Griffiss.
Journal of Immunology (1991)

133 Citations

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