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Edith Gouin

Edith Gouin

Institut Pasteur
France

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Bacteria
  • Genetics

Edith Gouin mostly deals with Cell biology, Actin, Microbiology, Listeria monocytogenes and Paracytophagy. Her work carried out in the field of Actin brings together such families of science as Rac GTP-Binding Proteins and Motility. Her studies in Microbiology integrate themes in fields like Listeria and Cytoskeleton.

Her work in Listeria monocytogenes is not limited to one particular discipline; it also encompasses Virulence. Her Virulence research includes themes of Pathogen, Vacuole, Intracellular parasite and Innate immune system. Her Paracytophagy study integrates concerns from other disciplines, such as Cytoplasm and Arp2/3 complex.

Her most cited work include:

  • L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. (691 citations)
  • Actin-based motility of intracellular pathogens. (324 citations)
  • A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii. (227 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Microbiology, Listeria monocytogenes, Cell biology, Virulence and Listeria. Her studies deal with areas such as Internalin, Immune system, Intracellular parasite and Small interfering RNA as well as Microbiology. Edith Gouin interconnects Pathogen, Gene and Innate immune system in the investigation of issues within Listeria monocytogenes.

Her Cell biology research is multidisciplinary, incorporating elements of Actin cytoskeleton and Cytokinesis. Specifically, her work in Virulence is concerned with the study of Virulence factor. Her study focuses on the intersection of Listeria and fields such as Intracellular with connections in the field of Biofilm and Intestinal mucosa.

She most often published in these fields:

  • Microbiology (134.57%)
  • Listeria monocytogenes (134.57%)
  • Cell biology (80.25%)

What were the highlights of her more recent work (between 2011-2020)?

  • Microbiology (134.57%)
  • Listeria monocytogenes (134.57%)
  • Virulence (79.01%)

In recent papers she was focusing on the following fields of study:

Edith Gouin spends much of her time researching Microbiology, Listeria monocytogenes, Virulence, Pathogen and Cell biology. Her research integrates issues of Immune system and Intracellular parasite in her study of Microbiology. Her research in Listeria monocytogenes is mostly focused on Listeria.

In her study, Innate immune system, Regulation of gene expression and Pathogenicity island is inextricably linked to Virulence factor, which falls within the broad field of Listeria. Her work in Pathogen covers topics such as Gene which are related to areas like Listeriolysin O. Her biological study spans a wide range of topics, including Mitotic exit and Arp2/3 complex.

Between 2011 and 2020, her most popular works were:

  • Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity. (133 citations)
  • Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity. (133 citations)
  • Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity. (133 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Bacteria
  • Genetics

Listeria monocytogenes, Virulence, Pathogen, Gene and Genetics are her primary areas of study. The study of Listeria monocytogenes is intertwined with the study of Microbiology in a number of ways. The concepts of her Microbiology study are interwoven with issues in Intestinal mucosa, Intracellular, Intracellular parasite, Biofilm and Motility.

In the subject of general Gene, her work in Transposable element, Transcription, Mutant and Frameshift mutation is often linked to Riboswitch, thereby combining diverse domains of study. Her Genetics and Mutation, Listeria, Genome, Whole genome sequencing and Trans-acting investigations all form part of her Genetics research activities.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein.

C. Kocks;E. Gouin;M. Tabouret;P. Berche.
Cell (1992)

1000 Citations

Actin-based motility of intracellular pathogens.

Edith Gouin;Matthew D Welch;Pascale Cossart.
Current Opinion in Microbiology (2005)

450 Citations

Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated.

J Mengaud;S Dramsi;E Gouin;Jose A Vazquez-Boland.
Molecular Microbiology (1991)

332 Citations

The RickA protein of Rickettsia conorii activates the Arp2/3 complex

Edith Gouin;Coumaran Egile;Pierre Dehoux;Véronique Villiers.
Nature (2004)

294 Citations

A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii.

E. Gouin;H. Gantelet;C. Egile;I. Lasa.
Journal of Cell Science (1999)

283 Citations

Listeria monocytogenes evades killing by autophagy during colonization of host cells.

Cheryl L. Birmingham;Veronica Canadien;Edith Gouin;Erin B. Troy.
Autophagy (2007)

275 Citations

Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures

Serge Mostowy;Serge Mostowy;Serge Mostowy;Matteo Bonazzi;Matteo Bonazzi;Matteo Bonazzi;Mélanie Anne Hamon;Mélanie Anne Hamon;Mélanie Anne Hamon;To Nam Tham;To Nam Tham;To Nam Tham.
Cell Host & Microbe (2010)

250 Citations

The unrelated surface proteins ActA of Listeria monocytogenes and lcsA of Shigella flexneri are sufficient to confer actin‐based motility on Listeria innocua and Escherichia coli respectively

C. Kocks;C. Kocks;J.‐B. Marchand;E. Gouin;H. D'Hauteville.
Molecular Microbiology (1995)

245 Citations

Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity.

Christophe Bécavin;Christophe Bécavin;Christophe Bécavin;Christiane Bouchier;Pierre Lechat;Cristel Archambaud;Cristel Archambaud;Cristel Archambaud.
Mbio (2014)

243 Citations

Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

Flavia Castellano;Philippe Montcourrier;Jean-Claude Guillemot;Edith Gouin.
Current Biology (1999)

236 Citations

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